Evidence map›Paper›PMID 29568681›Full record

ArticleBrain and behavior2018

Role of sLOX-1 in intracranial artery stenosis and in predicting long-term prognosis of acute ischemic stroke.

Xian-Mei Li, Ping-Ping Jin, Jie Xue, Jie Chen, Qin-Fen Chen, Xiao-Qian Luan, Zeng-Rui Zhang, Tie-Er Yu, Zheng-Yi Cai, Kai Zhao and 1 more

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Observational
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Soluble Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Level is Related to Clinical Prognosis In Patients with Acute Atherosclerosis-related Ischemic Stroke.Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xian-Mei LiDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Ping-Ping JinDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Jie XueDepartment of Neurology Yangpu Hospital of Tongji University Shang Hai China.ORCID 0000-0001-8699-0831
Jie ChenDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Qin-Fen ChenDepartment of Gastroenterology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Xiao-Qian LuanDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Zeng-Rui ZhangDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Tie-Er YuDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Zheng-Yi CaiDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Kai ZhaoDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.
Bei ShaoDepartment of Neurology First Affiliated Hospital of Wenzhou Medical University Wenzhou China.ORCID 0000-0002-0304-3052
Wenzhou Medical University · CNYangpu Hospital of Tongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The role of sLOX-1 in acute ischemic stroke still remains unclear. This study aims to demonstrate the value of sLOX-1 in evaluating degrees of intracranial artery stenosis and to predict prognosis in stroke. Methods: Two hundred and seventy-two patients were included in this study and basic data were collected within 72 hr on admission. We assessed the association between sLOX-1 levels and stroke conditions in one-year duration. After adjusting for potential confounders, regression analyses were performed. Results: We found that sLOX-1 levels were increased significantly in severe patients compared to the mild stroke group ( Conclusions: Our study demonstrated that sLOX-1 levels could be used to evaluate the severity of stroke and the degrees of intracranial artery stenosis. Furthermore, sLOX-1 could be exploited to predict the long-term functional outcome of stroke.

Indexed as

BiomarkersBrain IschemiaConstriction, PathologicFemaleFollow-Up StudiesHumansIntracranial Arterial DiseasesMaleMiddle AgedPrognosisScavenger Receptors, Class EStrokeBiomarkersOLR1 protein, humanScavenger Receptors, Class Eacute ischemic strokeintracranial artery stenosislong‐term functional outcomeSerum soluble lectin‐like oxidized low‐density lipoprotein receptor‐1

Identifiers

PMID29568681
PMCPMC5853620
OpenAlexW2771150440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.