ArticleSouthern African journal of HIV medicine2016
Barriers to adherence to antiretroviral treatment in a regional hospital in Vredenburg, Western Cape, South Africa.
Article in Southern African journal of HIV medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 84 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
84 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Pooled it
- Pooled it
- The effect of disclosure on adherence to antiretroviral therapy among adults living with HIV in Ethiopia: a systematic review and meta-analysis.BMC infectious diseases · 2019Pooled it
- Predictors of Treatment Adherence and Virological Failure Among People Living with HIV Receiving Antiretroviral Therapy in a South African Rural Community: A Sub-study of the ITREMA Randomised Clinical Trial.AIDS and behavior · 2023Trial
- Depression management and antiretroviral treatment outcome among people living with HIV in Northwest and East regions of Cameroon.BMC infectious diseases · 2022Trial
- Factors influencing improved adherence and retention among men living with human immunodeficiency virus in sub-Saharan Africa: A scoping review.African journal of primary health care & family medicine · 2026Article
- Barriers to Antiretroviral Therapy Adherence Among Children in Ekurhuleni, South Africa: A Descriptive Study.International journal of environmental research and public health · 2026Article
- Evaluating the relationship between adherence to antiretroviral therapy and health-related quality of life among people living with HIV/AIDS in Northwestern Nigeria.BMC public health · 2026Article
- Perceptions of adolescents and young adults failing antiretroviral therapy on adherence in Gauteng, South Africa.Southern African journal of HIV medicine · 2026Article
- Demographic and Socioeconomic Factors Associated With ART Nonadherence Among 15 Years and Older South Africans. Evidence From the 2022 Cross-Sectional Population-Based Household Survey.AIDS research and treatment · 2026Article
- Adherence to ART medication refill pick-up in the regional hospital HIV clinics at the Sekhukhune district in Limpopo province, South Africa: a retrospective cohort study.BMJ public health · 2026Article
- Developing a cognitive behavioral therapy for adherence and depression-based group counseling models to enhance antiretroviral medication adherence in human immunodeficiency virus/acquired immune deficiency syndrome patients.Journal of education and health promotion · 2026Review
- Factors influencing men to discontinue antiretroviral at Seventh Day Adventist clinic, Maseru, Lesotho.Frontiers in public health · 2026Article
- Effect of rapid antiretroviral therapy initiation on loss to follow-up, virologic failure, and immunologic failure among people living with HIV under the treat-all policy in China: a retrospective cohort study (2016-2023).Frontiers in medicine · 2026Article
- A scoping review of mobile health for ART adherence in pregnant and breastfeeding women with HIV in sub-Saharan Africa: preferences, acceptability, and privacy concerns.BMC infectious diseases · 2025Article
- Correlates of virological non-suppression among children and adolescents aged 5-19 years on Dolutegravir-based regimens attending Gulu regional referral hospital, Northern Uganda: a mixed methods cross-sectional study.BMC infectious diseases · 2025Article
- Non-disclosure of Known HIV Status among People Living with HIV in the Mozambique Population-Based HIV Impact Assessment (INSIDA 2021).AIDS and behavior · 2025Article
- Using positive deviance to enhance HIV care retention in South Africa: development of a compassion-focused program to improve the staff and patient experience.BMC global and public health · 2025Article
- Beliefs of Pentecostal pastors on the use of antiretroviral treatment among Pentecostal Christians living with HIV in a suburb of Cape Town-South Africa: a community health systems lens.Health policy and planning · 2025Article
- "Ashamed of being seen in an HIV clinic": a qualitative analysis of barriers to engaging in HIV care from the perspectives of patients and healthcare workers in the Daraja clinical trial.BMC public health · 2025Article
24 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSouth Africa currently runs the largest public antiretroviral treatment (ART) programme in the world, with over 80% of people living with HIV and/or AIDS on ART. However, in order to appreciate the benefits of using ART, patients are subject to uncompromising and long-term commitments of taking at least 95% of their treatment as prescribed. Evidence shows that this level of adherence is seldom achieved because of a multilevel and sometimes interwoven myriad of factors.
objectiveWe described the challenges faced by patients on ART in Vredenburg with regard to ART adherence.
methodsA descriptive qualitative research design was used. Eighteen non-adhering patients on ART in the Vredenburg regional hospital were purposefully selected. Using a semi-structured interview guide, we conducted in-depth interviews with the study participants in their mother tongue (Afrikaans). The interviews were audio-taped, transcribed verbatim and translated into English. The data were analysed manually using the thematic content analysis method.
resultsStigma, disclosure, unemployment, lack of transport, insufficient feeding, disability grants and alternative forms of therapy were identified as major barriers to adherence, whereas inadequate follow-ups and lack of patient confidentiality came under major criticisms from the patients.
conclusionInterventions to address poverty, stigma, discrimination and disclosure should be integrated with group-based ART adherence models in Vredenburg while further quantitative investigations should be carried out to quantify the extent to which these factors impede adherence in the community.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.