Evidence map›Paper›PMID 29568424›Full record

ArticleChemical science2017

Optical control of GPR40 signalling in pancreatic β-cells.

James Allen Frank, Dmytro A Yushchenko, Nicholas H F Fine, Margherita Duca, Mevlut Citir, Johannes Broichhagen, David J Hodson, Carsten Schultz, Dirk Trauner

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Fine-tuned photochromic sulfonylureas for optical control of beta cell CaDiabetic medicine : a journal of the British Diabetic Association · 2023
    Article
  4. Review
  5. Chemical Tools for Lipid Cell Biology.Accounts of chemical research · 2023
    Article
  6. Article
  7. Article
  8. Photoswitchable Serotonins for Optical Control of the 5-HTAngewandte Chemie (International ed. in English) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Optical Control of Lysophosphatidic Acid Signaling.Journal of the American Chemical Society · 2020
    Article
  14. Article
  15. Review
  16. Optical control of L-type CaNature chemical biology · 2018
    Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 6 countries.

James Allen FrankDepartment of Chemistry , Center for Integrated Protein Science , Ludwig Maximilians University Munich , Butenandtstraße 5-13 , 81377 Munich , Germany.ORCID 0000-0001-6705-2540
Dmytro A YushchenkoEuropean Molecular Biology Laboratory (EMBL) , Cell Biology & Biophysics Unit , Meyerhofstraße 1 , 69117 Heidelberg , Germany . Email: schultz@embl.de.ORCID 0000-0003-0355-6197
Nicholas H F FineInstitute of Metabolism and Systems Research (IMSR) , University of Birmingham , Birmingham , B15 2TT , UK . Email: d.hodson@bham.ac.uk.ORCID 0000-0003-2343-8534
Margherita DucaDepartment of Chemistry , Center for Integrated Protein Science , Ludwig Maximilians University Munich , Butenandtstraße 5-13 , 81377 Munich , Germany.ORCID 0000-0002-3527-6328
Mevlut CitirEuropean Molecular Biology Laboratory (EMBL) , Cell Biology & Biophysics Unit , Meyerhofstraße 1 , 69117 Heidelberg , Germany . Email: schultz@embl.de.
Johannes BroichhagenDepartment of Chemistry , Center for Integrated Protein Science , Ludwig Maximilians University Munich , Butenandtstraße 5-13 , 81377 Munich , Germany.ORCID 0000-0003-3084-6595
David J HodsonInstitute of Metabolism and Systems Research (IMSR) , University of Birmingham , Birmingham , B15 2TT , UK . Email: d.hodson@bham.ac.uk.ORCID 0000-0002-8641-8568
Carsten SchultzEuropean Molecular Biology Laboratory (EMBL) , Cell Biology & Biophysics Unit , Meyerhofstraße 1 , 69117 Heidelberg , Germany . Email: schultz@embl.de.
Dirk TraunerDepartment of Chemistry , Center for Integrated Protein Science , Ludwig Maximilians University Munich , Butenandtstraße 5-13 , 81377 Munich , Germany.ORCID 0000-0002-6782-6056
Center for Integrated Protein Science Munich · DEUniversity of Nottingham · GBCzech Academy of Sciences, Institute of Organic Chemistry and Biochemistry · CZOregon Health & Science University · USUniversity of Milan · IT

Funding

Medical Research Council MR/N00275X/1Wellcome Trust
6 · The paper itself

Abstract

Fatty acids activate GPR40 and K

Identifiers

PMID29568424
PMCPMC5848828
OpenAlexW2751759563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.