Evidence map›Paper›PMID 29568273›Full record

ArticleFrontiers in physiology2018

Regular Aerobic, Resistance, and Cross-Training Exercise Prevents Reduced Vascular Function Following a High Sugar or High Fat Mixed Meal in Young Healthy Adults.

Emon K Das, Pui Y Lai, Austin T Robinson, Joan Pleuss, Mohamed M Ali, Jacob M Haus, David D Gutterman, Shane A Phillips

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Mechanisms of Atherosclerosis Induced by Postprandial Lipemia.Frontiers in cardiovascular medicine · 2021
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Emon K DasDepartment of Medicine, Cardiovascular Center and Clinical Research Center, Medical College of Wisconsin, Milwaukee, WI, United States.
Pui Y LaiDepartment of Medicine, Cardiovascular Center and Clinical Research Center, Medical College of Wisconsin, Milwaukee, WI, United States.
Austin T RobinsonDepartment of Physical Therapy, University of Illinois, Chicago, IL, United States.
Joan PleussDepartment of Medicine, Cardiovascular Center and Clinical Research Center, Medical College of Wisconsin, Milwaukee, WI, United States.
Mohamed M AliDepartment of Physical Therapy, University of Illinois, Chicago, IL, United States.
Jacob M HausDepartment of Kinesiology and Nutrition, University of Illinois, Chicago, IL, United States.
David D GuttermanDepartment of Medicine, Cardiovascular Center and Clinical Research Center, Medical College of Wisconsin, Milwaukee, WI, United States.
Shane A PhillipsDepartment of Medicine, Cardiovascular Center and Clinical Research Center, Medical College of Wisconsin, Milwaukee, WI, United States.
Medical College of Wisconsin · USUniversity of Illinois Chicago · USUniversity of Illinois Urbana-Champaign · US

Funding

ZONISMIDE IN THE TREATMENT OF SEIZURES IN PATIENTSM01RR000058 · NCRR · MEDICAL COLLEGE OF WISCONSIN · PI BROUSSEAU, DAVID C · 1985 to 2006
$19.9M
Effects of Low Carbohydrate and Low Fat Diets on Endothelium Function in ObesityR01HL095701 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PHILLIPS, SHANE A · 2010 to 2014
$2.1M
Mechanisms of exertional hypertension and vascular dysfunctionK23HL085614 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI PHILLIPS, SHANE A · 2007 to 2011
$645k
NCRR NIH HHS M01 RR000058NHLBI NIH HHS K23 HL085614NHLBI NIH HHS R01 HL095701
6 · The paper itself

Abstract

The postprandial state can negatively influence flow mediated dilation (FMD), a predictor of atherosclerosis and cardiovascular disease. This investigation was designed to determine the effect of regular aerobic and/or resistance exercise on postprandial FMD after a high sugar or high fat mixed meal. Forty-five healthy participants were recruited from one of four groups: lean sedentary (SED), runners, weight lifters, and cross-trainers. Participants were randomly crossed over to a high sugar meal (HSM) and a high fat mixed meal (HFMM; both fat and carbohydrate). Pre-and postprandial endothelial function was assessed for both meals using brachial artery FMD. Plasma lipids, insulin, glucose, hs-CRP, and SOD were also measured with both meals. Endothelium-independent dilation was determined via sublingual nitroglycerin. Brachial artery FMD was reduced in SED following the HSM (9.9 ± 0.9% at baseline, peak reduction at 60 min 6.5 ± 1.0%) and the HFMM (9.4 ± 0.9% at baseline, peak reduction at 120 min 5.9 ± 1.2%;

Indexed as

arteriosclerosisdietary carbohydratesdietary fatsendotheliumpostprandial lipemiaregular exercisevascularvasodilation

Identifiers

PMID29568273
PMCPMC5853082
OpenAlexW2793062173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.