ArticleWorld journal of gastroenterology2018
Differing profiles of people diagnosed with acute and chronic hepatitis B virus infection in British Columbia, Canada.
Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 25 citations in OpenAlex.
- Addressing digital exclusion to improve access to HIV and viral hepatitis care for people who experience criminalization: a mixed methods evaluation of a quality improvement project.International journal for equity in health · 2025Article
- Ethnic Disparities in Extrahepatic Manifestations Among People With HCV Infection: A Population-Based Study in British Columbia.Open forum infectious diseases · 2025Article
- National hepatitis B and C estimates for 2021: Measuring Canada's progress towards eliminating viral hepatitis as a public health concern.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025Article
- Susceptibility to Hepatitis B Virus Infection Among People Who Inject Drugs in Montreal, Canada.Drug and alcohol review · 2025Article
- Association of hepatitis B virus treatment with all-cause and liver-related mortality among individuals with HBV and cirrhosis: a population-based cohort study.Lancet regional health. Americas · 2024Article
- Canadian Association for the Study of the Liver Single Topic Conference on Hepatitis B Virus: 'Progress toward hepatitis B elimination in Canada'.Canadian liver journal · 2024Article
- Prevalence of Hepatitis B in Canadian First-Time Blood Donors: Association with Social Determinants of Health.Viruses · 2024Article
- Hepatitis B Blood Donor Screening Data: An Under-Recognized Resource for Canadian Public Health Surveillance.Viruses · 2023Article
- Hepatitis B and C virus infections and associated factors among HIV-positive and HIV-negative tuberculosis patients in public health facilities, Northeast Ethiopia: A comparative cross-sectional study.SAGE open medicine · 2023Article
- Article
- Chronic hepatitis C infection is associated with higher incidence of extrahepatic cancers in a Canadian population based cohort.Frontiers in oncology · 2022Article
- Article
- Acute Hepatitis B Infection After a Switch to Long-Acting Cabotegravir and Rilpivirine.Open forum infectious diseases · 2020Article
- Concurrent Hepatitis C and B Virus and Human Immunodeficiency Virus Infections Are Associated With Higher Mortality Risk Illustrating the Impact of Syndemics on Health Outcomes.Open forum infectious diseases · 2020Article
- Impacts of hepatitis B and hepatitis C co-infection with tuberculosis, a prospective cohort study.Virology journal · 2020Article
- Syndemic Characterization of HCV, HBV, and HIV Co-infections in a Large Population Based Cohort Study.EClinicalMedicineArticle
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo describe the characteristics of people diagnosed with acute and chronic hepatitis B virus (HBV) infection in British Columbia (BC).
methodsWe used data from the BC Hepatitis Testers Cohort (BC-HTC), which includes all individuals tested for hepatitis C virus (HCV) or human immunodeficiency virus (HIV) or those diagnosed with HBV or active tuberculosis in BC since 1990. These data were integrated with prescription drug, medical visit, hospitalization and mortality data. HBV cases were classified as acute or chronic according to provincial guidelines. We compared characteristics of individuals by HBV infection group (acute, chronic and negative). Factors associated with acute or chronic HBV infection were assessed with multinomial logistic regression models in comparison to the HBV negative group.
results46498 of the 1058056 eligible BC-HTC participants were diagnosed with HBV infection. 4.3% of HBV positive individuals were diagnosed with acute HBV infections while 95.7% had chronic infections. Problematic alcohol use, injection drug use, and HIV or HCV co-infection were more common among individuals diagnosed with acute HBV compared to those with chronic infections and HBV negative individuals. In multivariable multinomial logistic regression models, we observed significant associations between acute or chronic HBV diagnosis and being male, age at HBV diagnosis or birth cohort, South and East Asian ethnicity, HCV or HIV infection, and injection drug use. The odds of acute HBV decreased with increasing age among people who inject drugs, while the opposite was true for chronic HBV. Persons with acute HBV were predominantly White (78%) while those with chronic HBV were mostly East Asian (60%). Relative to Whites, East Asians had 12 times greater odds of being diagnosed with chronic HBV infection. These odds increased with increasing socioeconomic deprivation.
conclusionDifferences in the profiles of people diagnosed with acute and chronic HBV infection necessitate differentiated screening, prevention, care and treatment programs.
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