Evidence map›Paper›PMID 29568200›Full record

ArticleWorld journal of gastroenterology2018

Holger Schäffler, Maria Rohde, Sarah Rohde, Astrid Huth, Nicole Gittel, Hannes Hollborn, Dirk Koczan, Änne Glass, Georg Lamprecht, Robert Jaster

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  7. Genetic association analysis ofWorld journal of gastroenterology · 2020
    Observational
  8. Review
  9. Polymorphisms inAnnals of gastroenterology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Holger SchäfflerDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Maria RohdeDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Sarah RohdeDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Astrid HuthDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Nicole GittelDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Hannes HollbornDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Dirk KoczanInstitute of Immunology, Rostock University Medical Center, Rostock 18057, Germany.
Änne GlassInstitute for Biostatistics and Informatics in Medicine and Ageing Research, Rostock 18057, Germany.
Georg LamprechtDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany.
Robert JasterDepartment of Medicine II, Division of Gastroenterology, Rostock University Medical Center, Rostock 18057, Germany. robert.jaster@med.uni-rostock.de.
University of Rostock · DEInstitute for ImplantTechnology and Biomaterials · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate disease-specific gene expression profiles of peripheral blood mononuclear cells (PBMCs) from Crohn's disease (CD) patients in clinical remission.

methodsPatients with CD in clinical remission or with very low disease activity according to the Crohn's disease activity index were genotyped regarding nucleotide-binding oligomerization domain 2 (

resultsEmploying microarray assays, a total of 267 genes were identified that were significantly up- or downregulated in PBMCs of WT-

conclusionOur data identify

Indexed as

AdultCells, CulturedCrohn DiseaseDown-RegulationFemaleGene Expression ProfilingHumansLectins, C-TypeLeukocytes, MononuclearMaleMiddle AgedMuramidaseMutationNod2 Signaling Adaptor ProteinOligonucleotide Array Sequence AnalysisReceptors, Cell SurfaceCLEC5A protein, humanLectins, C-TypeMuramidaseNOD2 protein, humanNod2 Signaling Adaptor ProteinReceptors, Cell SurfaceTREM1 protein, humanTriggering Receptor Expressed on Myeloid Cells-1CLEC5ACrohn’s diseaseGene expressionLysozymeNOD2Peripheral blood mononuclear cells

Identifiers

PMID29568200
PMCPMC5859222
OpenAlexW2791071470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.