ArticleInternational journal of obesity (2005)2018
Lifestyle of women before pregnancy and the risk of offspring obesity during childhood through early adulthood.
Article in International journal of obesity (2005), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Risk Factors in the First 1000 Days of Life Associated With Childhood Obesity: A Systematic Review and Risk Factor Quality Assessment.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Pooled it
- The effects of bariatric surgery on periconception maternal health: a systematic review and meta-analysis.Human reproduction update · 2021Pooled it
- Lifestyle Modifications Prior to Pregnancy and Their Impact on Maternal and Perinatal Outcomes: A Review.Journal of clinical medicine · 2025Review
- Maternal macronutrient intake at pregnancy and offspring growth trajectory through childhood: a prospective analysis in the Growing Up Today Study 2 cohort.The American journal of clinical nutrition · 2025Article
- The Impact of Parental Behaviors on Children's Lifestyle, Dietary Habits, Screen Time, Sleep Patterns, Mental Health, and BMI: A Scoping Review.Children (Basel, Switzerland) · 2025Review
- Parental adherence to healthy lifestyles in relation to the risk of obesity in offspring: A prospective cohort study in China.Journal of global health · 2023Article
- Unsupervised clustering analysis of comprehensive health status and its influencing factors on women of childbearing age: a cross-sectional study from a province in central China.BMC public health · 2023Article
- Pre-pregnancy Diet to Maternal and Child Health Outcome: A Scoping Review of Current Evidence.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2023Article
- Maternal consumption of ultra-processed foods and subsequent risk of offspring overweight or obesity: results from three prospective cohort studies.BMJ (Clinical research ed.) · 2022Article
- Association between maternal shift work during pregnancy child overweight and metabolic outcomes in early childhood.Frontiers in public health · 2022Article
- Maternal diet quality during pregnancy is associated with biomarkers of metabolic risk among male offspring.Diabetologia · 2021Article
- Observational
- Pregestational BMI and higher offspring's risk of overweight/obesity in smoker and non-smoker mothers.Public health nutrition · 2021Article
- Associations between a maternal healthy lifestyle score and adverse offspring birth outcomes and childhood obesity in the Lifeways Cross-Generation Cohort Study.International journal of obesity (2005) · 2020Article
- Dietary Diversity and Micronutrients Adequacy in Women of Childbearing Age: Results from ELANS Study.Nutrients · 2020Article
- Melatonin profiles during the third trimester of pregnancy and health status in the offspring among day and night workers: A case series.Neurobiology of sleep and circadian rhythms · 2019Article
- Night Shift Work Before and During Pregnancy and Offspring Weight Outcomes Through Adolescence.Obesity (Silver Spring, Md.) · 2018Article
- Developmental Origins of Disease: Emerging Prenatal Risk Factors and Future Disease Risk.Current epidemiology reports · 2018Article
- Association between maternal adherence to healthy lifestyle practices and risk of obesity in offspring: results from two prospective cohort studies of mother-child pairs in the United States.BMJ (Clinical research ed.) · 2018Article
Corrections and comments
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Authors and funding
10 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundIn women, adhering to an overall healthy lifestyle is associated with a dramatically reduced risk of cardio-metabolic disorders. Whether such a healthy lifestyle exerts an intergenerational effects on child health deserves examination.
methodsWe included 5701 children (9-14 years old at baseline) of the Growing Up Today Study 2, and their mothers, who are participants in the Nurses' Health Study II. Pre-pregnancy healthy lifestyle was defined as a normal body mass index, no smoking, physical activity ≥150 min/week, and diet in the top 40% of the Alternative Healthy Eating Index-2010. Obesity during childhood and adolescence was defined using the International Obesity Task Force age- and sex-specific cutoffs. Multivariable log-binominal regression models with generalized estimating equations were used to evaluate the association of pre-pregnancy healthy lifestyle and offspring obesity.
resultsWe identified 520 (9.1%) offspring who became obese during follow-up. A healthy body weight of mothers and no smoking before pregnancy was significantly associated with a lower risk of obesity among offspring: the relative risks [RRs; 95% confidence intervals (CIs)] were 0.37 (0.31-0.43) and 0.64 (0.49-0.84), respectively. Eating a healthy diet and regular moderate-to-vigorous physical activities were inversely related to offspring obesity risk, but these relations were not statistically significant. Compared to children of mothers who did not meet any low-risk lifestyle factors, offspring of women who adhered to all four healthy lifestyle factors had 75% lower risk of obesity (RR: 0.25, 95% CI: 0.14-0.43).
conclusionAdherence to an overall healthy lifestyle before pregnancy is strongly associated with a low risk of offspring obesity in childhood, adolescence, and early adulthood. These findings highlight the importance of an overall healthy lifestyle before pregnancy as a potential strategy to prevent obesity in future generations.
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