Evidence map›Paper›PMID 29568042›Full record

ArticleScientific reports2018

Artifact Rejection Methodology Enables Continuous, Noninvasive Measurement of Gastric Myoelectric Activity in Ambulatory Subjects.

Armen A Gharibans, Benjamin L Smarr, David C Kunkel, Lance J Kriegsfeld, Hayat M Mousa, Todd P Coleman

Registry-linked trialOpen access · goldAbstract readValidation Study
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05789511 (High Resolution Electrogastrography), which is not on this map. Cited by 34 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 2 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05789511 unknown statusnot on this mapstarted 2022, after this paper: background citation

High Resolution Electrogastrography (HR-EGG) Assessment in Medically Refractory Gastroparesis

TypeobservationalSponsorUniversity of VirginiaRan2022 to 2025Enrolled40ConditionsGastroparesis, Lung Transplant, ComplicationsArmsHigh Resolution Electrogastography
3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 2 syntheses or guidelines pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Review
  5. Review
  6. Review
  7. [A New Paradigm in Diagnosing Functional Gastroduodenal Disorders: High-Resolution Electrogastrography].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2024
    Review
  8. Data augmentation for generating synthetic electrogastrogram time series.Medical & biological engineering & computing · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Gastric AlimetryJournal of clinical medicine · 2023
    Review
  16. Review
  17. Article
  18. Comparison of Gastric AlimetryScientific reports · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Armen A GharibansDepartment of Bioengineering, University of California at San Diego, La Jolla, CA, United States.
Benjamin L SmarrDepartment of Psychology, University of California at Berkeley, Berkeley, CA, United States.
David C KunkelGI Motility & Physiology Program, University of California at San Diego, La Jolla, CA, United States.
Lance J KriegsfeldDepartment of Psychology, University of California at Berkeley, Berkeley, CA, United States.
Hayat M MousaDepartment of Pediatrics, University of California at San Diego, La Jolla, CA, United States.
Todd P ColemanDepartment of Bioengineering, University of California at San Diego, La Jolla, CA, United States. tpcoleman@ucsd.edu.
University of California, San Diego · USUniversity of California, Berkeley · US

Funding

Integrative Bioengineering of Heart, Vessels, and BloodT32HL105373 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CHIEN, SHU, INTAGLIETTA, MARCOS · 2010 to 2019
$3.6M
6 · The paper itself

Abstract

The increasing prevalence of functional and motility gastrointestinal (GI) disorders is at odds with bottlenecks in their diagnosis, treatment, and follow-up. Lack of noninvasive approaches means that only specialized centers can perform objective assessment procedures. Abnormal GI muscular activity, which is coordinated by electrical slow-waves, may play a key role in symptoms. As such, the electrogastrogram (EGG), a noninvasive means to continuously monitor gastric electrical activity, can be used to inform diagnoses over broader populations. However, it is seldom used due to technical issues: inconsistent results from single-channel measurements and signal artifacts that make interpretation difficult and limit prolonged monitoring. Here, we overcome these limitations with a wearable multi-channel system and artifact removal signal processing methods. Our approach yields an increase of 0.56 in the mean correlation coefficient between EGG and the clinical "gold standard", gastric manometry, across 11 subjects (p < 0.001). We also demonstrate this system's usage for ambulatory monitoring, which reveals myoelectric dynamics in response to meals akin to gastric emptying patterns and circadian-related oscillations. Our approach is noninvasive, easy to administer, and has promise to widen the scope of populations with GI disorders for which clinicians can screen patients, diagnose disorders, and refine treatments objectively.

Indexed as

ArtifactsSignal Processing, Computer-AssistedAdolescentChildElectromyographyFemaleGastrointestinal DiseasesGastrointestinal MotilityHumansMaleManometryMobile ApplicationsMonitoring, AmbulatorySmartphoneStomachWearable Electronic Devices

Identifiers

PMID29568042
PMCPMC5864836
OpenAlexW2795095500

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.