Evidence map›Paper›PMID 29567832›Full record

ArticleThe Journal of biological chemistry2018

Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice.

Olga V Belyaeva, Lizhi Wu, Igor Shmarakov, Peter S Nelson, Natalia Y Kedishvili

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

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  14. Carotenoid metabolism at the intestinal barrier.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Olga V BelyaevaFrom the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Lizhi WuFrom the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294.
Igor Shmarakovthe Department of Medicine, Columbia University, New York, New York 21007.
Peter S Nelsonthe Departments of Urology and Medicine, University of Washington, Seattle, Washington 98195, and.
Natalia Y KedishviliFrom the Department of Biochemistry and Molecular Genetics, Schools of Medicine and Dentistry, University of Alabama at Birmingham, Birmingham, Alabama 35294, nkedishvili@uab.edu.
University of Alabama at Birmingham · USColumbia University · USFred Hutch Cancer Center · US

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Kirk Michael Habegger · 2013 to 2026
$19.5M
Postprandial Vitamin AR01DK068437 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S · 2004 to 2023
$7.0M
SHORT-CHAIN DEHYDROGENASES IN RETINOL/STEROL METABOLISMR01AA012153 · NIAAA · UNIVERSITY OF MISSOURI KANSAS CITY · PI KEDISHVILI, NATALIA Y · 2000 to 2017
$5.1M
Short-Chain Dehydrogenases in Retinol/Sterol MetabolismR01AR076924 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KEDISHVILI, NATALIA Y · 2020 to 2024
$2.2M
Vitamin A Homeostasis: Retinyl Ester StoresR01DK101251 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BLANER, WILLIAM S, HARRISON, EARL HOWARD · 2016 to 2018
$1.4M
NCI NIH HHS P30 CA013148NIAAA NIH HHS R01 AA012153NIAMS NIH HHS R01 AR076924NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK068437NIDDK NIH HHS R01 DK101251
6 · The paper itself

Abstract

Retinol dehydrogenase 11 (RDH11) is a microsomal short-chain dehydrogenase/reductase that recognizes all-

Indexed as

Animalsbeta CaroteneDietFemaleGene ExpressionHomeostasisMaleMiceMice, KnockoutMicrosomesMicrosomes, LiverOxidoreductasesRetinaldehydeRetinol-Binding Proteins, PlasmaSignal TransductionTestisbeta CaroteneOxidoreductasesRbp4 protein, mouseRdh11 protein, mouseRetinaldehydeRetinol-Binding Proteins, PlasmaVitamin Acarotenoiddehydrogenasereductaseretinaldehyderetinoic acidretinolvitamin A

Identifiers

PMID29567832
PMCPMC5936824
OpenAlexW2789292769

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.