Evidence map›Paper›PMID 29567781›Full record

ArticleHaematologica2018

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a

Alice S Mims, Anjali Mishra, Shelley Orwick, James Blachly, Rebecca B Klisovic, Ramiro Garzon, Alison R Walker, Steven M Devine, Katherine J Walsh, Sumithira Vasu and 11 more

Open access · goldAbstract readClinical Trial, Phase I
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. The rocky road to personalized medicine in acute myeloid leukaemia.Journal of cellular and molecular medicine · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 4 institutions in 1 country.

Alice S MimsDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH alice.mims@osumc.edu.
Anjali MishraDepartment of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Shelley OrwickDepartment of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
James BlachlyDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Rebecca B KlisovicDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA.
Ramiro GarzonDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Alison R WalkerDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Steven M DevineDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Katherine J WalshDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Sumithira VasuDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Susan WhitmanDepartment of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Guido MarcucciDepartment of Hematology and Hematopoietic Cell Transplantation, City of Hope National Medical Center, Duarte, CA.
Daniel JonesDepartment of Pathology, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Nyla A HeeremaDepartment of Pathology, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Gerard LozanskiDepartment of Pathology, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Michael A CaligiuriDepartment of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Clara D BloomfieldDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
John C ByrdDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
Richard PiekarzInvestigational Drug Branch of CTEP, National Cancer Institute, Bethesda, MD, USA.
Michael R GreverDivision of Hematology, Department of Medicine, The Ohio State University and The Ohio State University Comprehensive Cancer Center, Columbus, OH.
William BlumDepartment of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta, GA.
The Ohio State University · USEmory University · USCity Of Hope National Medical Center · USNational Cancer Institute · US

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Tasleem J Padamsee · 1985 to 2026
$132.3M
UM1 Supplement for Early Therapeutic Trials with Phase 2 IntentUM1CA186712 · NCI · OHIO STATE UNIVERSITY · PI SUSANNE M ARNOLD, WILLIAM E. CARSON · 2014 to 2026
$19.3M
SPORE Leukemia Tissue BankP50CA140158 · NCI · OHIO STATE UNIVERSITY · PI BLOOMFIELD, CLARA D · 2009 to 2013
$11.2M
PHASE I TRIALS OF ANTICANCER AGENTSU01CA076576 · NCI · OHIO STATE UNIVERSITY · PI GREVER, MICHAEL R · 1998 to 2013
$9.1M
NCI NIH HHS P30 CA016058NCI NIH HHS P50 CA140158NCI NIH HHS U01 CA076576NCI NIH HHS UM1 CA186712
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene DuplicationTandem Repeat SequencesAdultAntineoplastic Combined Chemotherapy ProtocolsBiomarkersDrug ResistanceFemaleHistone-Lysine N-MethyltransferaseHumansLeukemia, Myeloid, AcuteMaleMiddle AgedMyeloid-Lymphoid Leukemia ProteinRecurrenceRetreatmentYoung AdultBiomarkersHistone-Lysine N-MethyltransferaseKMT2A protein, humanMyeloid-Lymphoid Leukemia Protein

Identifiers

PMID29567781
PMCPMC6058798
OpenAlexW2791581028

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.