Evidence map›Paper›PMID 29567774›Full record

ArticleHaematologica2018

Lenalidomide results in a durable complete remission in acute myeloid leukemia accompanied by persistence of somatic mutations and a T-cell infiltrate in the bone marrow.

Dhruv Bansal, Kiran Vij, Gue Su Chang, Christopher A Miller, John F DiPersio, Ravi Vij, Sharon E Heath, Peter Westervelt, John S Welch, Todd A Fehniger

Abstract readCase ReportsLetter
In one paragraph

Article in Haematologica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Dhruv BansalDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA.
Kiran VijDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA.
Gue Su ChangMcDonnell Genome Institute, Washington University School of Medicine, Saint Louis, MO, USA.
Christopher A MillerMcDonnell Genome Institute, Washington University School of Medicine, Saint Louis, MO, USA.
John F DiPersioDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA.
Ravi VijDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA.
Sharon E HeathDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA.
Peter WesterveltDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA.
John S WelchDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA tfehnige@wustl.edu jwelch@wustl.edu.
Todd A FehnigerDepartment of Medicine, Division of Oncology, BMT and Leukemia Program, Washington University School of Medicine, Saint Louis, MO, USA tfehnige@wustl.edu jwelch@wustl.edu.

Funding

Specimen Acquistition and Expression ProfilingP01CA101937 · NCI · WASHINGTON UNIVERSITY · PI LEY, TIMOTHY J. · 2003 to 2023
$58.8M
Targeting the Bone Marrow Microenvironment In Acute Lymphocytic LeukemiaP50CA171963 · NCI · WASHINGTON UNIVERSITY · PI TODD A FEHNIGER · 2013 to 2026
$31.6M
TRANSLATING NK CELL BIOLOGY INTO CLINICAL CANCER IMMUNOTHERAPYR01CA205239 · NCI · WASHINGTON UNIVERSITY · PI FEHNIGER, TODD A · 2017 to 2020
$2.4M
RETINOIDS IN HEMATOPOIESISR01HL128447 · NHLBI · WASHINGTON UNIVERSITY · PI WELCH, JOHN S · 2016 to 2020
$1.9M
COMPREHENSIVE INFORMATIC ANALYSES OF AML GENOMES AND EPIGENOMESR50CA211782 · NCI · WASHINGTON UNIVERSITY · PI Christopher A Miller · 2017 to 2026
$1.5M
NCI NIH HHS P01 CA101937NCI NIH HHS P50 CA171963NCI NIH HHS R01 CA205239NCI NIH HHS R50 CA211782NHLBI NIH HHS R01 HL128447
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

MutationAgedBone MarrowFemaleHumansLenalidomideLeukemia, Myeloid, AcuteLymphocytes, Tumor-InfiltratingRemission InductionT-LymphocytesTreatment OutcomeLenalidomide

Identifiers

PMID29567774
PMCPMC6058793

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.