ArticleGenome research2018
Cancer-associated rs6983267 SNP and its accompanying long noncoding RNA
Open access · bronzeAbstract read
In one paragraph
Article in Genome research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 2 pooled it
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
41 citing papers in PubMed, 2 syntheses or guidelines pooled it, 65 citations in OpenAlex.
- The landscape of GWAS validation; systematic review identifying 309 validated non-coding variants across 130 human diseases.BMC medical genomics · 2022Pooled it
- The single nucleotide polymorphisms of interleukin-10 are associated with the risk of leukaemia: Evidence from 18 case-control studies.Medicine · 2020Pooled it
- Inflammation-related polymorphisms IFNG-AS1 rs1558744 and CCAT2 rs6983267: Potential risk factors for ulcerative colitis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Article
- Exploring the Role of Long Noncoding RNAs (lncRNAs) as Biomarkers in Cancers.Experientia supplementum (2012) · 2026Review
- Associations of CCAT2 gene polymorphisms with neuroblastoma susceptibility in children from Jiangsu province.European journal of medical research · 2025Article
- DNA Methylation in Ph-Negative Myeloproliferative Neoplasms: Prognostic Role and Therapeutic Implications.Current issues in molecular biology · 2025Review
- Putrescine can inhibit germinal center B cell differentiation by inducing reactive oxygen species generation.Indian journal of pharmacology · 2024Article
- Epigenetic methylation changes: implication as biomarkers in oral and maxillofacial area cancers.Medicine and pharmacy reports · 2023Article
- Evaluating the association of rs6983267 polymorphism of theMolecular biology research communications · 2023Article
- Classical Angiogenic Signaling Pathways and Novel Anti-Angiogenic Strategies for Colorectal Cancer.Current issues in molecular biology · 2022Review
- Of mice and human-specific long noncoding RNAs.Mammalian genome : official journal of the International Mammalian Genome Society · 2022Review
- Targeting non-coding RNAs to overcome cancer therapy resistance.Signal transduction and targeted therapy · 2022Review
- The Roles of the Colon Cancer Associated Transcript 2 (CCAT2) Long Non-Coding RNA in Cancer: A Comprehensive Characterization of the Tumorigenic and Molecular Functions.International journal of molecular sciences · 2021Review
- CCAT2 enhances autophagy-related invasion and metastasis via regulating miR-4496 and ELAVL1 in hepatocellular carcinoma.Journal of cellular and molecular medicine · 2021Article
- Contributions of HOTAIR polymorphisms to the susceptibility of cancer.International journal of clinical oncology · 2021Article
- Genetic variant rs10251977 (G>A) in EGFR-AS1 modulates the expression of EGFR isoforms A and D.Scientific reports · 2021Article
- Investigating the association between rs6983267 polymorphism and susceptibility to gastrointestinal cancers in Iranian population.Molecular biology reports · 2021Article
- 8q24.21 Locus: A Paradigm to Link Non-Coding RNAs, Genome Polymorphisms and Cancer.International journal of molecular sciences · 2021Review
- Editing and Chemical Modifications on Non-Coding RNAs in Cancer: A New Tale with Clinical Significance.International journal of molecular sciences · 2021Review
- The Long Noncoding RNA CCAT2 Induces Chromosomal Instability Through BOP1-AURKB Signaling.Gastroenterology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
44 authors at 8 institutions in 6 countries.
Maitri Y ShahDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Manuela FerracinDepartment of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, 40126 Bologna, Italy.
Valentina PileczkiDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Baoqing ChenDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Roxana RedisDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Linda FabrisDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Xinna ZhangCenter for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Cristina IvanCenter for RNA Interference and Non-coding RNAs, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Masayoshi ShimizuDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Cristian Rodriguez-AguayoDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Mihnea DragomirDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Katrien Van RoosbroeckDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Maria Ines AlmeidaDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Maria CicconeDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Daniela NedelcuDepartment of Oncology-Pathology, Karolinska Institute, Cancer Center Karolinska, SE-171 77 Stockholm, Sweden.
Maria Angelica CortezDepartment of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Taghi ManshouriDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Steliana CalinDepartment of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Muharrem MuftuogluDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Pinaki P BanerjeeDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Mustafa H BadiwiDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Jan Parker-ThornburgDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Asha MultaniDepartment of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
James William WelshDepartment of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Marcos Roberto EstecioDepartment of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Hui LingDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Ciprian TomuleasaThe Research Center for Functional Genomics, Biomedicine and Translational Medicine, Iuliu Hatieganu University of Medicine and Pharmacy, 400012 Cluj Napoca, Romania.
Delia DimaDepartment of Hematology, The Oncology Institute Ion Chiricuta, 400015 Cluj Napoca, Romania.
Hui YangDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Hector AlvarezDepartment of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
M James YouDepartment of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Milan RadovichCenter for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA.
Elizabeth ShpallDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Muller FabbriDepartments of Pediatrics and Molecular Microbiology and Immunology, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Children's Center for Cancer and Blood Diseases and The Saban Research Institute, Children's Hospital Los Angeles, Los Angeles, California 90027, USA.
Katy RezvaniDepartment of Stem Cell Transplantation and Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Leonard GirnitaDepartment of Oncology-Pathology, Karolinska Institute, Cancer Center Karolinska, SE-171 77 Stockholm, Sweden.
Ioana Berindan-NeagoeDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Anirban MaitraDepartment of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Srdan VerstovsekDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Riccardo FoddeDepartment of Pathology, Erasmus MC Cancer Institute, Erasmus University Medical Center, 3015 CE Rotterdam, The Netherlands.
Carlos Bueso-RamosDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Mihai GageaDepartment of Veterinary Medicine and Surgery, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
Guillermo Garcia ManeroDepartment of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
George A CalinDepartment of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77054, USA.
The University of Texas MD Anderson Cancer Center · USKarolinska University Hospital · SEErasmus MC · NLIndiana University School of MedicineInstitute of Oncology Prof. Dr. Ion Chiricuta · ROIuliu Hațieganu University of Medicine and Pharmacy · ROUniversity of Bologna · ITUniversity of Southern California · US
Funding
University of Texas M.D. Anderson Cancer SPORE-LeukemiaP50CA100632 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI KONOPLEVA, MARINA Y · 2003 to 2023
$43.7MTropism Enhanced Oncolytic Adenovirus for the Treatment of Brain TumorsP50CA127001 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Juan Fueyo · 2008 to 2026
$41.2MUT M.D. Anderson Cancer Center SPORE in MelanomaP50CA093459 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI GRIMM, ELIZABETH A · 2004 to 2014
$23.7MGenetic Epidemiology of non-Hodgkin LymphomaR01CA200703 · NCI · MAYO CLINIC ROCHESTER · PI CERHAN, JAMES R · 2016 to 2020
$3.3MProtein-coding and non-coding RNA biomarkers for early detection of CLLR01CA182905 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI ABRUZZO, LYNNE V., CALIN, GEORGE A. · 2014 to 2018
$2.9MCHARACTERIZATION AND TARGETED THERAPY OF T-ALL DEFICIENT FOR PTEN AND INK4A/ARFR01CA164346 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YOU, M. JAMES · 2012 to 2015
$1.2MNovel extra cellular RNA-based combinatorial RNA inhibition therapyUH2TR000943 · NCATS · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI CALIN, GEORGE A., LOPEZ-BERESTEIN, GABRIEL · 2013 to 2014
$1.1MNCATS NIH HHS UH2 TR000943NCI NIH HHS P50 CA093459NCI NIH HHS P50 CA100632NCI NIH HHS P50 CA127001NCI NIH HHS R01 CA164346NCI NIH HHS R01 CA182905NCI NIH HHS R01 CA200703
Abstract
The cancer-risk-associated rs6983267 single nucleotide polymorphism (SNP) and the accompanying long noncoding RNA
Indexed as
AdultAgedAged, 80 and overAnimalsCell Line, TumorCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMaleMiceMice, TransgenicMiddle AgedMyelodysplastic-Myeloproliferative DiseasesPolymorphism, Single NucleotideRNA Editinglong non-coding RNA CCAT2, humanRNA, Long Noncoding
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.