Evidence map›Paper›PMID 29567671›Full record

ArticleDevelopment (Cambridge, England)2018

Control of the proportion of inner cells by asymmetric divisions and the ensuing resilience of cloned rabbit embryos.

Dimitri Fabrèges, Nathalie Daniel, Véronique Duranthon, Nadine Peyriéras

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Dimitri FabrègesBioEmergences Laboratory, CNRS USR 3695, 91190 Gif-sur-Yvette, France.ORCID 0000-0001-6603-1510
Nathalie DanielUMR BDR, INRA, ENVA, Université Paris Saclay, 78350, Jouy en Josas, France.ORCID 0000-0002-2251-1296
Véronique DuranthonUMR BDR, INRA, ENVA, Université Paris Saclay, 78350, Jouy en Josas, France.
Nadine PeyriérasBioEmergences Laboratory, CNRS USR 3695, 91190 Gif-sur-Yvette, France nadine.peyrieras@cnrs.fr.ORCID 0000-0002-4905-6414
Centre National de la Recherche Scientifique · FRÉcole Nationale Vétérinaire d'Alfort · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mammalian embryo cloning by nuclear transfer has a low success rate. This is hypothesized to correlate with a high variability of early developmental steps that segregate outer cells, which are fated to extra-embryonic tissues, from inner cells, which give rise to the embryo proper. Exploring the cell lineage of wild-type embryos and clones, imaged

Indexed as

Asymmetric Cell DivisionAnimalsBlastocyst Inner Cell MassCell CountCell DeathCell DifferentiationCell LineageCell ProliferationCloning, OrganismComputer SimulationEmbryonic DevelopmentFemaleGreen Fluorescent ProteinsImaging, Three-DimensionalMaleMicroscopy, Fluorescence, Multiphotonenhanced green fluorescent proteinGreen Fluorescent Proteins3D+time 2-photon imagingAsymmetrical divisionsCell deathDigital specimensIn silico experimentationRabbit pre-implantation developmentSomatic cell nuclear transferSpatial cell segregation

Identifiers

PMID29567671
PMCPMC5964649
OpenAlexW2793620563

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.