Evidence map›Paper›PMID 29567658›Full record

ArticleGenetics2018

Establishment of Signaling Interactions with Cellular Resolution for Every Cell Cycle of Embryogenesis.

Long Chen, Vincy Wing Sze Ho, Ming-Kin Wong, Xiaotai Huang, Lu-Yan Chan, Hon Chun Kaoru Ng, Xiaoliang Ren, Hong Yan, Zhongying Zhao

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Delineating the mechanisms and design principles ofComputational and structural biotechnology journal · 2022
    Review
  7. Article
  8. Article
  9. Initial characterization of gap phase introduction in every cell cycle ofFrontiers in cell and developmental biology · 2022
    Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Long ChenDepartment of Electronic Engineering, City University of Hong Kong, China.
Vincy Wing Sze HoDepartment of Biology, Hong Kong Baptist University, China.
Ming-Kin WongDepartment of Biology, Hong Kong Baptist University, China.ORCID 0000-0002-4088-3819
Xiaotai HuangSchool of Computer Science and Technology, Xidian University, Xi'an, 710126 China.
Lu-Yan ChanDepartment of Biology, Hong Kong Baptist University, China.
Hon Chun Kaoru NgDepartment of Biology, Hong Kong Baptist University, China.
Xiaoliang RenDepartment of Biology, Hong Kong Baptist University, China.
Hong YanDepartment of Electronic Engineering, City University of Hong Kong, China.
Zhongying ZhaoDepartment of Biology, Hong Kong Baptist University, China zyzhao@hkbu.edu.hk.ORCID 0000-0003-2743-9008
Hong Kong Baptist University · HKCity University of Hong Kong · HKXidian University · CN

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Intercellular signaling interactions play a key role in breaking fate symmetry during animal development. Identification of signaling interactions at cellular resolution is technically challenging, especially in a developing embryo. Here, we develop a platform that allows automated inference and validation of signaling interactions for every cell cycle of

Indexed as

Cell CycleEmbryonic DevelopmentSignal TransductionAnimalsAnimals, Genetically ModifiedBiomarkersCaenorhabditis elegansCell CommunicationCell LineageDrosophila ProteinsGene DosageProtein BindingReceptors, NotchReproducibility of ResultsTransgenesBiomarkersDrosophila ProteinsN protein, DrosophilaReceptors, NotchC. elegansCell contactcell lineagedivision asymmetryNotch signaling

Identifiers

PMID29567658
PMCPMC5937172
OpenAlexW2793367246

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.