ArticleAJNR. American journal of neuroradiology2018
Diagnosing Early Ischemic Changes with the Latest-Generation Flat Detector CT: A Comparative Study with Multidetector CT.
Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Stroke Evaluation in the Interventional Suite Using Dual-Layer Detector Cone-Beam CT: a First-in-human Prospective Cohort Study (the Next Generation X-ray Imaging System Trial).Clinical neuroradiology · 2024Trial
- Brain cone-beam CT image quality improvement using a deep-learning-based denoising method: a multicenter retrospective study.Neuroradiology · 2026Article
- Diagnostic Accuracy of Ischemia and Hemorrhage on Cone-Beam CT Immediately After Endovascular Thrombectomy.Stroke (Hoboken, N.J.) · 2026Article
- Sine spin flat-detector CT for enhanced brain parenchyma visualization: an intraindividual comparison on a latest-generation angiography system.Neuroradiology · 2026Article
- One-Stop Management Improves Outcome for Large Vessel Occlusion Stroke.Stroke (Hoboken, N.J.) · 2026Article
- Size and location of intracranial hemorrhage in acute stroke presentations: correlation with baseline NIHSS and relevance to direct-to-angiography workflows.Frontiers in neurology · 2026Article
- Direct to hybrid CT-angiosuite (Nexaris) reduces treatment time for stroke thrombectomy (Direct-ST): A prospective simulation study.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Utilization of flat-panel detector computed tomography for evaluation of COVID-19 pneumonia during neurointerventional procedures.Tuberkuloz ve toraks · 2024Article
- Sine Spin flat detector CT can improve cerebral soft tissue imaging: a retrospective in vivo study.European radiology experimental · 2024Article
- Why Does It Shine?-A Prognostic Analysis about Predisposing Factors for Blood-Brain Barrier Damage after Revascularisation of Cerebral Large-Vessel Occlusion.Journal of cardiovascular development and disease · 2023Article
- Can flat-detector CT after successful endovascular treatment predict long-term outcome in patients with large vessel occlusion? An Alberta Stroke Programme Early CT Score-based study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Review
- The butterfly effect: improving brain cone-beam CT image artifacts for stroke assessment using a novel dual-axis trajectory.Journal of neurointerventional surgery · 2023Article
- Evaluation of Sine Spin flat detector CT imaging compared with multidetector CT.Journal of neurointerventional surgery · 2023Article
- Effective dose to patient measurements for flat-detector computed tomography protocols in acute stroke care.European radiology · 2020Article
- Validation of collateral scoring on flat-detector multiphase CT angiography in patients with acute ischemic stroke.PloS one · 2018Article
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9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
background and purposeOne-stop management of mechanical thrombectomy-eligible patients with large-vessel occlusion represents an innovative approach in acute stroke treatment. This approach reduces door-to-reperfusion times by omitting multidetector CT, using flat detector CT as pre-mechanical thrombectomy imaging. The purpose of this study was to compare the diagnostic performance of the latest-generation flat detector CT with multidetector CT. MATERIALS AND
methodsProspectively derived data from patients with ischemic stroke with large-vessel occlusion and mechanical thrombectomy were analyzed in this monocentric study. All included patients underwent multidetector CT before referral to our comprehensive stroke center and flat detector CT in the angiography suite before mechanical thrombectomy. Diagnosis of early ischemic signs, quantified by the ASPECTS, was compared between modalities using cross tables, the Pearson correlation, and Bland-Altman plots. The predictive value of multidetector CT- and flat detector CT-derived ASPECTS for functional outcome was investigated using area under the receiver operating characteristic curve analysis.
resultsOf 25 patients, 24 (96%) had flat detector CT with sufficient diagnostic quality. Median multidetector CT and flat detector CT ASPECTSs were 7 (interquartile range, 5.5-9 and 4.25-8, respectively) with a mean period of 143.6 ± 49.5 minutes between both modalities. The overall sensitivity was 85.1% and specificity was 83.1% for flat detector CT ASPECTS compared with multidetector CT ASPECTS as the reference technique. Multidetector CT and flat detector CT ASPECTS were strongly correlated (
conclusionsDetermination of ASPECTS on flat detector CT is feasible, showing no significant difference compared with multidetector CT ASPECTS and a similar predictive value for functional outcome. Our findings support the use of flat detector CT for emergency stroke imaging before mechanical thrombectomy to reduce door-to-groin time.
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