Evidence map›Paper›PMID 29567455›Full record

ArticleChild abuse & neglect2018

Modeling life course pathways from adverse childhood experiences to adult mental health.

Tiffany M Jones, Paula Nurius, Chiho Song, Christopher M Fleming

Abstract read
In one paragraph

Article in Child abuse & neglect, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.

0numbers the graph read from it
0cells of the map it votes in
64citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

64 citing papers in PubMed.

  1. Trial
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  3. Comparing childhood, chronic, and recent adversity on internalizing symptoms and hypothalamic-pituitary-adrenal axis functioning.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
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  18. Trauma as a mediator of childhood adversity and mental illness in South Africa: A path analysis.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2025
    Article
  19. Article
  20. Article

4 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tiffany M JonesSchool of Social Work, University of Washington, Seattle, United States. Electronic address: tjones03@uw.edu.
Paula NuriusSchool of Social Work, University of Washington, Seattle, United States. Electronic address: nurius@uw.edu.
Chiho SongSchool of Social Work, University of Washington, Seattle, United States. Electronic address: chsong79@uw.edu.
Christopher M FlemingSchool of Social Work, University of Washington, Seattle, United States. Electronic address: cmf45@uw.edu.

Funding

Methods and Data CoreR24HD042828 · NICHD · UNIVERSITY OF WASHINGTON · PI CURRAN, SARA R. · 2002 to 2016
$9.3M
NICHD NIH HHS R24 HD042828
6 · The paper itself

Abstract

Although the association between adverse childhood experiences (ACEs) and adult mental health is becoming well established, less is known about the complex and multiple pathways through which ACEs exert their influence. Growing evidence suggests that adversity early in life conveys not only early impacts, but also augments risk of stress-related life course cascades that continue to undermine health. The present study aims to test pathways of stress proliferation and stress embodiment processes linking ACEs to mental health impairment in adulthood. Data are from the 2011 Behavioral Risk Factor Surveillance Survey, a representative sample of Washington State adults ages 18 and over (N = 14,001). Structural equation modeling allowed for testing of direct and indirect effects from ACEs though low income status, experiences of adversity in adulthood, and social support. The model demonstrated that adult low income, social support and adult adversity are in fact conduits through which ACEs exert their influence on mental health impairment in adulthood. Significant indirect pathways through these variables supported hypotheses that the effect of ACEs is carried through these variables. This is among the first models that demonstrates multiple stress-related life course pathways through which early life adversity compromises adult mental health. Discussion elaborates multiple service system opportunities for intervention in early and later life to interrupt direct and indirect pathways of ACE effects.

Indexed as

Adverse Childhood ExperiencesMental HealthSocial SupportStress, PsychologicalAdultChildFemaleHumansMaleMental DisordersModels, PsychologicalPovertyRisk FactorsWashingtonAdverse childhood experiencesMental healthStress embodimentStress proliferationTrauma

Identifiers

PMID29567455
PMCPMC5953821

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.