Evidence map›Paper›PMID 29567222›Full record

ArticleJournal of food and drug analysis2018

Thyme essential oils from Spain: Aromatic profile ascertained by GC-MS, and their antioxidant, anti-lipoxygenase and antimicrobial activities.

Ana-Belen Cutillas, Alejandro Carrasco, Ramiro Martinez-Gutierrez, Virginia Tomas, Jose Tudela

Open access · hybridAbstract read
In one paragraph

Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
7.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 83 citations in OpenAlex.

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  15. Antibacterial, Antioxidant, andEvidence-based complementary and alternative medicine : eCAM · 2023
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  16. Life (Basel, Switzerland) · 2022
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  19. Molecules (Basel, Switzerland) · 2022
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  20. Plants (Basel, Switzerland) · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ana-Belen CutillasGENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, Spain1.
Alejandro CarrascoGENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, Spain1.
Ramiro Martinez-GutierrezNovozymes Spain S.A., Madrid, Spain2.
Virginia TomasDepartment of Analytical Chemistry, University of Murcia, Spain.
Jose TudelaGENZ-Group of Research on Enzymology, Department of Biochemistry and Molecular Biology-A, Regional Campus of International Excellence "Campus Mare Nostrum", University of Murcia, Spain1.
Universidad de Murcia · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Six samples of red thyme (Thymus zygis) and two samples of winter thyme (Thymus hyemalis) essential oils (EOs) were obtained from plants cultivated in south-eastern Spain and extracted by steam distillation. Analysis by gas chromatography coupled with mass spectrometry detection provided the relative (%) and absolute (mM) concentrations. Thymol (30-54%), p-cymene (14-27%) and γ-terpinene (8-28%) were the most abundant components of T. zygis EO, while 1,8-Cineole (3-37%), p-cymene (1-29%), linalool (8-13%) and thymol (0-19%) were the most abundant components in the case of T. hyemalis EO. Enantioselective gas chromatography identified (-)-linalool, (-)-borneol and (+)-limonene as the main enantiomers. Several methods to evaluate antioxidant capacities were applied to the EOs, concluding that their activities were mainly due to thymol and linalool. The inhibition of lipoxygenase activity, mainly due to thymol, p-cymene and linalool, suggested their possible use as anti-inflammatories. The high antibacterial and antifungal activities determined for the EOs means that they can be used as natural preservatives. The results support the potential use of Thymus sp. EOs as natural food, cosmetic and pharmaceutical ingredients.

Indexed as

Anti-Infective AgentsAntioxidantsBacteriaCandidaGas Chromatography-Mass SpectrometryLipoxygenaseLipoxygenase InhibitorsOils, VolatileSpainThymus PlantAnti-Infective AgentsAntioxidantsLipoxygenaseLipoxygenase InhibitorsOils, VolatileAntioxidantsLipoxygenase inhibitorsMicrobial sensitivity testsOilsThymus plantVolatile

Identifiers

PMID29567222
PMCPMC9322249
OpenAlexW2626372732

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.