ArticleJournal of food and drug analysis2018
Bioactive polyphenols in kinkéliba tea (Combretum micranthum) and their glucose-lowering activities.
Article in Journal of food and drug analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 45 citations in OpenAlex.
- Polyphenol-rich tea decreases iron absorption from fortified wheat bread in Senegalese mother-child pairs and bioavailability of ferrous fumarate is sharply lower in children.European journal of clinical nutrition · 2020Trial
- Ethanolic Extract of Kinkeliba (International journal of molecular sciences · 2025Article
- An Overview on Flavor Extraction, Antimicrobial and Antioxidant Significance, and Production of Herbal Wines.ACS omega · 2024Review
- Anti-cholinesterase, anti-inflammatory and antioxidant properties ofIBRO neuroscience reports · 2023Article
- Kinkéliba (Molecules (Basel, Switzerland) · 2023Article
- Ethnopharmacology, Antimicrobial Potency, and Phytochemistry of AfricanAntibiotics (Basel, Switzerland) · 2023Review
- Review
- 4-Hydroxybenzoic Acid as an Antiviral Product from Alkaline Autoxidation of Catechinic Acid: A Fact to Be Reviewed.Plants (Basel, Switzerland) · 2022Article
- Fruit pomaces-their nutrient and bioactive components, effects on growth and health of poultry species, and possible optimization techniques.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2022Review
- Autoxidation Products of the Methanolic Extract of the Leaves ofMolecules (Basel, Switzerland) · 2022Article
- Traditional medicinal plants used for treating emerging and re-emerging viral diseases in northern Nigeria.European journal of integrative medicine · 2022Article
- Antimicrobial Activity ofJournal of inflammation research · 2021Article
- Antityrosinase Activity ofMolecules (Basel, Switzerland) · 2020Article
- Article
- Antioxidant and nephroprotection activities ofHeliyon · 2019Article
- Curculigoside and polyphenol-rich ethyl acetate fraction of Molineria latifolia rhizome improved glucose uptake via potential mTOR/AKT activated GLUT4 translocation.Journal of food and drug analysis · 2018Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Herbal tea kinkéliba prepared from the leaves of Combretum micranthum has been widely consumed in West African countries for its flavor, nutritional and medicinal properties. Under bio-guided screening, the kinkéliba leaves were chemically investigated using various chromatographic and spectrometric methods that led to the identification of thirteen different flavonoid compounds. Further biological tests illustrated that the identified compounds may have synergistic effects to decrease the expression of phosphoenolpyruvate carboxykinase (PEPCK) mRNA and glucose production in an H4IIE hepatoma cell line, indicating its potential use for insulin-resistant diabetes treatment. Further in vivo study on C57BL/6J mice indicates that kinkéliba can lower plasma glucose levels in a dose-dependent manner without significant weight loss and toxicity. The ethyl acetate extract in rich of flavonoids could also increase the glucose tolerance (GT) after seven weeks' administrations. Both in vitro and in vivo experiments support a potential new application of kinkéliba leaves as an anti-diabetes agent.
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