ArticleCanadian journal of diabetes2018
Early-Onset Physical Frailty in Adults With Diabesity and Peripheral Neuropathy.
Article in Canadian journal of diabetes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Frailty measurement, prevalence, incidence, and clinical implications in people with diabetes: a systematic review and study-level meta-analysis.The lancet. Healthy longevity · 2020Pooled it
- Multimodal Rehabilitative Outcome Measures of Fatigue in Patients with Diabetic Neuropathy.Brain sciences · 2026Article
- Measuring changes in prevalence of hypertension and diabetes across 720 districts in India using cross-sectional data from 2016 to 2021.BMJ public health · 2025Article
- Prevalence and Factors Associated With Frailty Among Older Adults Living With HIV Compared to Their Uninfected Peers From the Kenyan Coast.International journal of public health · 2024Article
- Major adverse foot events and functional mobility deficits associated with diabetic neuropathy and nephropathy.Metabolism and target organ damage · 2024Article
- Intramedullary Nail Fixation by Suprapatellar and Infrapatellar Approaches for Treatment of Distal Tibial Fractures.Orthopaedic surgery · 2022Article
- The Development and Concurrent Validity of a Multi-Sensor-Based Frailty Toolkit for In-Home Frailty Assessment.Sensors (Basel, Switzerland) · 2022Article
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- Challenges and Strategies for Diabetes Management in Community-Living Older Adults.Diabetes spectrum : a publication of the American Diabetes Association · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
objectivesDiabesity (obesity and diabetes mellitus) has been identified as a potential contributor to early-onset frailty. Impairments contributing to early onset of physical frailty in this population are not well understood, and there is little evidence of the impact of peripheral neuropathy on frailty. The purpose of this study was to determine impairments that contribute to early-onset physical frailty in individuals with diabesity and peripheral neuropathy.
methodsWe studied 105 participants, 82 with diabesity and peripheral neuropathy (57 years of age, body mass index [BMI] 31 kg/m
resultsParticipants with diabesity and peripheral neuropathy were 7.4 times more likely to be classified as physically frail. Impairments in lower-extremity function were associated with classification of frailty.
conclusionsIndividuals with diabesity and peripheral neuropathy are particularly likely to be classified as frail. Earlier identification and interventions aimed at improving lower-extremity function may be important to mitigate the early-onset functional decline.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.