ArticleAustralian critical care : official journal of the Confederation of Australian Critical Care Nurses2018
Face and content validity of variables associated with the difficult-to-sedate child in the paediatric intensive care unit: A survey of paediatric critical care clinicians.
Article in Australian critical care : official journal of the Confederation of Australian Critical Care Nurses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00814099 (Sedation Management in Pediatric Patients With Acute Respiratory Failure), which is not on this map. Cited by 9 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Sedation Management in Pediatric Patients With Acute Respiratory Failure
Who cites it
9 citing papers in PubMed.
- Initial Psychometric Testing of a Pain Quality Pictogram Tool Among Hmong Limited English Proficient and Bilingual Community Members and Healthcare Practitioners.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2024Article
- Enteral Pentobarbital in the Difficult to Sedate Critically Ill Children.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2024Article
- Analgesia and sedation in critically ill pediatric patients: an update from the recent guidelines and point of view.European journal of pediatrics · 2023Review
- Article
- Validating a measure of anticipated sex work-related stigma among male and female sex workers in Kenya.Global public health · 2022Article
- Recommendations for analgesia and sedation in critically ill children admitted to intensive care unit.Journal of anesthesia, analgesia and critical care · 2022Review
- Content and Face Validation of a Novel, Interactive Nutrition Specific Physical Exam Competency Tool (INSPECT) to Evaluate Registered Dietitians' Competence: A Delphi Consensus from the United States.Healthcare (Basel, Switzerland) · 2021Article
- Developing and Establishing Content Validity of Vignettes for Health Care Education and Research.Western journal of nursing research · 2021Article
- "Difficult to Sedate": Successful Implementation of a Benzodiazepine-Sparing Analgosedation-Protocol in Mechanically Ventilated Children.Children (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
backgroundClinicians recognise that some critically ill children are difficult-to-sedate. It may be possible to identify this clinical phenotype for sedation response using statistical modelling techniques adopted from machine learning. This requires identification of a finite number of variables to include in the statistical model.
objectiveTo establish face and content validity for 17 candidate variables identified in the international literature as characteristic of the difficult-to-sedate child phenotype.
methodsPaediatric critical care clinicians rated the relevance of 17 variables characterising the difficult-to-sedate child using a four-point scale ranging from not (1) to highly relevant (4). Face and content validity of these variables were assessed by calculating a mean score for each item and computing an item-level content validity index. Items with a mean score >1 were rated as having adequate face validity. An item-level content validity index ≥0.70 indicated good to excellent content validity. SETTING AND
participantsWeb-based survey emailed to members of the Pediatric Acute Lung Injury and Sepsis Investigators Network or the Society of Critical Care Medicine Pediatric Sedation Study Group.
resultsOf 411 possible respondents, 121 useable surveys were returned for a response rate of 29%. All items had a mean score >1, indicating adequate face validity. Ten of 17 items scored an item-level content validity index ≥0.70. The highest scoring items were requiring three or more sedation classes simultaneously, daily modal sedation score indicating agitation, sedation score indicating agitation for 2 consecutive hours, receiving sedatives at a dose >90th percentile of the usual starting dose, and receiving intermittent paralytic doses for sedation.
conclusionsComputation of an item-level content validity index validated variables to include in statistical modelling of the difficult-to-sedate phenotype. The results indicate consensus among paediatric critical care clinicians that the majority of candidate variables identified through literature review are characteristic of the difficult-to-sedate child.
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