ArticleFertility and sterility2018
Male sleep duration and fecundability in a North American preconception cohort study.
Article in Fertility and sterility, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Pooled it
- Effects of physical activity and sleep duration on fertility: A systematic review and meta-analysis based on prospective cohort studies.Frontiers in public health · 2022Pooled it
- Male cellular telephone exposure, fecundability, and semen quality: results from two preconception cohort studies.Human reproduction (Oxford, England) · 2021Pooled it
- Sleep restriction and testosterone concentrations in young healthy males: randomized controlled studies of acute and chronic short sleep.Sleep health · 2019Trial
- Circadian Disruption Is Associated with Elevated Whole-Semen mtDNA Copy Number and ImplicatesInternational journal of molecular sciences · 2026Article
- Disinfection Byproducts, Oxidative Stress, and Sleep Quality among Healthy Chinese Men.Environment & health (Washington, D.C.) · 2026Article
- Sleep variability and time to achieving pregnancy: findings from a pilot cohort study of women desiring pregnancy.Fertility and sterility · 2025Article
- Observational
- Association of sleep disturbances with diminished ovarian reserve in women undergoing infertility treatment.Scientific reports · 2024Article
- Preconception sleep duration, non-daytime work schedules, and incidence of spontaneous abortion: a prospective cohort study.Human reproduction (Oxford, England) · 2024Article
- Association between mental health and male fertility: depression, rather than anxiety, is linked to decreased semen quality.Frontiers in endocrinology · 2024Article
- Association of sleep traits with male fertility: a two-sample Mendelian randomization study.Frontiers in genetics · 2024Article
- Infertility in Men: Advances towards a Comprehensive and Integrative Strategy for Precision Theranostics.Cells · 2022Review
- The association between work hours, shift work, and job latitude with fecundability: A preconception cohort study.Journal of occupational health psychology · 2022Article
- Predictive models of pregnancy based on data from a preconception cohort study.Human reproduction (Oxford, England) · 2022Article
- Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review.Reproductive biology and endocrinology : RB&E · 2022Review
- Men's Sleep Quality and Assisted Reproductive Technology Outcomes in Couples Referred to a Fertility Clinic: A Chinese Cohort Study.Nature and science of sleep · 2022Article
- Poor Sleep Quality is an Independent Risk Factor for Acquired Premature Ejaculation.Nature and science of sleep · 2022Article
- Sleep Behavior and Self-Reported Infertility: A Cross-Sectional Analysis Among U.S. Women.Frontiers in endocrinology · 2022Article
- The potential impacts of circadian rhythm disturbances on male fertility.Frontiers in endocrinology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectiveTo evaluate prospectively the association between male sleep duration and fecundability.
designPregnancy Online Study (PRESTO), a Web-based prospective cohort study of North American couples enrolled during the preconception period (2013-2017).
settingNot applicable. PATIENT(S): Male participants were aged ≥21 years; female participants were aged 21-45 years. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): At enrollment, men reported their average nightly sleep duration in the previous month. Pregnancy status was updated on female follow-up questionnaires every 8 weeks for up to 12 months or until conception. Analyses were restricted to 1,176 couples who had been attempting to conceive for up to six cycles at enrollment. Proportional probabilities regression models were used to estimate fecundability ratios (FRs) and 95% confidence intervals (CIs), adjusting for potential confounders. RESULT(S): Relative to 8 hours per night of sleep, multivariable-adjusted FRs for <6, 6, 7, and ≥9 hours per night of sleep were 0.62 (95% CI 0.45-0.87), 1.06 (95% CI 0.87-1.30), 0.97 (95% CI 0.81-1.17), and 0.73 (95% CI 0.46-1.15), respectively. The association between short sleep duration (<6 hours per night) and fecundability was similar among men not working nights or rotating shifts (FR 0.60, 95% CI 0.41-0.88) and among men without a history of infertility (FR 0.62, 95% CI 0.44-0.87) and was stronger among fathers (FR 0.46, 95% CI 0.28-0.76). CONCLUSION(S): Short sleep duration in men was associated with reduced fecundability. Because male factor accounts for 50% of couple infertility, identifying modifiable determinants of infertility could provide alternatives to expensive fertility workups and treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.