Evidence map›Paper›PMID 29566719›Full record

ArticleJournal of nanobiotechnology2018

Functionalized rare earth-doped nanoparticles for breast cancer nanodiagnostic using fluorescence and CT imaging.

Akhil Jain, Pierrick G J Fournier, Vladimir Mendoza-Lavaniegos, Prakhar Sengar, Fernando M Guerra-Olvera, Enrique Iñiguez, Thomas G Kretzschmar, Gustavo A Hirata, Patricia Juárez

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.

  1. Pooled it
  2. Review
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  5. Article
  6. Article
  7. Biomedical Applications of Gadolinium-Containing Biomaterials: Not Only MRI Contrast Agent.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  8. Effect of EuRSC advances · 2025
    Article
  9. Review
  10. Article
  11. Synthesis and In Vitro Testing of YVOMolecules (Basel, Switzerland) · 2022
    Article
  12. Article
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Akhil JainBiomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Pierrick G J FournierBiomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Vladimir Mendoza-LavaniegosDepartamento de Geología, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Transpeninsular Ensenada-Tijuana #318, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Prakhar SengarBiomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Fernando M Guerra-OlveraBiomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Enrique IñiguezDepartamento de Geología, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Transpeninsular Ensenada-Tijuana #318, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Thomas G KretzschmarDepartamento de Geología, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Transpeninsular Ensenada-Tijuana #318, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico.
Gustavo A HirataUniversidad Nacional Autónoma de México (UNAM)-Centro de Nanociencias y Nanotecnología (CNyN), Km. 107 Carretera Tijuana-Ensenada, C.P. 22860, Ensenada, B.C., Mexico.
Patricia JuárezBiomedical Innovation Department, Centro de Investigación Científica y de Educación Superior de Ensenada (CICESE), Carretera Ensenada-Tijuana No. 3918, Zona Playitas, C.P. 22860, Ensenada, B.C., Mexico. pjuarez@cicese.mx.ORCID http://orcid.org/0000-0002-6305-5995
Centro de Investigación Científica y de Educación Superior de Ensenada · MXCETYS Universidad · MXUniversidad Nacional Autónoma de México · MX

Funding

CICESE 985-105Consejo Nacional de Ciencia y Tecnología 232608Consejo Nacional de Ciencia y Tecnología 247892Dirección General de Asuntos del Personal Académico, Universidad Nacional Autónoma de México IN111017
6 · The paper itself

Abstract

backgroundBreast cancer is the second leading cause of cancer death among women and represents 14% of death in women around the world. The standard diagnosis method for breast tumor is mammography, which is often related with false-negative results leading to therapeutic delays and contributing indirectly to the development of metastasis. Therefore, the development of new tools that can detect breast cancer is an urgent need to reduce mortality in women. Here, we have developed Gd

resultsGd

conclusionsOur findings provide significant evidence that could permit the future clinical application of FA-conjugated Gd

Indexed as

AnimalsBreast NeoplasmsCell Line, TumorEuropiumFemaleFolic AcidGadoliniumHEK293 CellsHeterograftsHumansInjections, IntravenousLuminescent MeasurementsMiceNanoparticlesParticle SizeTomography, X-Ray ComputedEuropiumFolic AcidGadoliniumBreast cancerCancer detectionFolate receptorLuminescent nanoparticles

Identifiers

PMID29566719
PMCPMC5863469
OpenAlexW2794680493

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.