Trial reportBMC pregnancy and childbirth2018
Accelerating newborn survival in Ghana through a low-dose, high-frequency health worker training approach: a cluster randomized trial.
Trial report in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Accelerating Newborn Survival in Ghana Through a Low-dose, High-frequency Health Worker Training Approach
Caring for Providers to Improve Patient Experience (CPIPE) Study: A Cluster Randomized-controlled Trial to Assess the Impact of the CPIPE Intervention on Person-centered Maternity Care
Who cites it
48 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Standardised formal resuscitation training programmes for reducing mortality and morbidity in newborn infants.The Cochrane database of systematic reviews · 2026Pooled it
- How can human resources for health interventions contribute to sexual, reproductive, maternal, and newborn healthcare quality across the continuum in low- and lower-middle-income countries? A systematic review.Human resources for health · 2021Pooled it
- Interventions to reduce preterm birth and stillbirth, and improve outcomes for babies born preterm in low- and middle-income countries: A systematic review.Journal of global health · 2021Pooled it
- Multi-professional simulation-based team training in obstetric emergencies for improving patient outcomes and trainees' performance.The Cochrane database of systematic reviews · 2020Pooled it
- The effects of interactive training of healthcare providers on the management of life-threatening emergencies in hospital.The Cochrane database of systematic reviews · 2019Pooled it
- Mono-Professional Simulation-Based Obstetric Training in a Low-Resource Setting: Stepped-Wedge Cluster Randomized Trial.JMIR medical education · 2025Trial
- Simulation-based low-dose, high-frequency plus mobile mentoring versus traditional group-based trainings among health workers on day of birth care in Nigeria; a cluster randomized controlled trial.BMC health services research · 2020Trial
- Trial
- Neonatal resuscitation skills retention among healthcare providers one year after implementation of in situ low-dose high-frequency simulations using innovative tools across two regions in Tanzania.Global health action · 2026Article
- Assessing basic Emergency Obstetric and Neonatal Care (BEmONC) service provision in community health centers: a mixed-methods study from Jember, Indonesia.BMC health services research · 2026Article
- Mortality impact of implementing maternal perinatal deaths surveillance and response quality-of-care improvement strategy for maternal and newborn care, northeast Namibia: a quasi-experimental study.Journal of global health · 2026Article
- Effectiveness of a novel midwifery preceptor program on midwives' competence and confidence in Sierra Leone: A prospective pilot study.PLOS global public health · 2026Article
- Impact of a long-term mentorship program for childbirth providers on quality of care: A cluster randomized controlled trial.PLOS global public health · 2026Article
- Key components of developing midwifery preceptors: a pathway to strengthen midwifery education and care in low resource settings.BMC global and public health · 2025Review
- Implementation of a midwifery preceptor program in Sierra Leone: a qualitative evaluation using the Consolidated Framework for Implementation Research.BMC global and public health · 2025Article
- Evaluation of immediate and sustained effects of transitioning quality long-acting reversible contraceptives (LARCs) services to public sector health facilities in Ghana: a pre-post intervention study.Reproductive health · 2025Article
- Article
- A policy in stagnation: addressing inequalities in the distribution of emergency obstetric and neonatal care in Ghana.Frontiers in global women's health · 2025Article
- The impact of educational interventions on the competence of nurses and midwives in neonatal resuscitation in sub-Saharan Africa: A systematic review.Journal of public health in Africa · 2025Review
- Development and initiation of a preceptor program to improve midwifery and nursing clinical education in sub-saharan Africa: protocol for a mixed methods study.BMC nursing · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundNewborn deaths comprise nearly half of under-5 deaths in Ghana, despite the fact that skilled birth attendants (SBAs) are present at 68% of births, which implies that evidence-based care during labor, birth and the immediate postnatal period may be deficient. We assessed the effect of a low-dose, high-frequency (LDHF) training approach on long-term evidence-based skill retention among SBAs and impact on adverse birth outcomes.
methodsFrom 2014 to 2017, we conducted a cluster-randomized trial in 40 hospitals in Ghana. Eligible hospitals were stratified by region and randomly assigned to one of four implementation waves. We assessed the relative risks (RRs) of institutional intrapartum stillbirths and 24-h newborn mortality in months 1-6 and 7-12 of implementation as compared to the historical control period, and in post-intervention facilities compared to pre-intervention facilities during the same period. All SBAs providing labor and delivery care were invited to enroll; their knowledge and skills were assessed pre- and post-training, and 1 year later.
resultsAdjusting for region and health facility type, the RR of 24-h newborn mortality in the 40 enrolled hospitals was 0·41 (95% CI 0·32-0·51; p < 0.001) in months 1-6 and 0·30 (95% CI 0·21-0·43; p < 0·001) in months 7-12 compared to baseline. The adjusted RR of intrapartum stillbirth was 0·64 (95% CI 0·53-0·77; p < 0·001) in months 1-6 and 0·48 (95% CI 0·36-0·63; p < 0·001) in months 7-12 compared to baseline. Four hundred three SBAs consented and enrolled. After 1 year, 200 SBAs assessed had 28% (95% CI 25-32; p < 0·001) and 31% (95% CI 27-36; p < 0·001) higher scores than baseline on low-dose 1 and 2 content skills, respectively.
conclusionsThis training approach results in a sustained decrease in facility-based newborn mortality and intrapartum stillbirths, and retained knowledge and skills among SBAs after a year. We recommend use of this approach for future maternal and newborn health in-service training and programs.
trial registrationRetrospectively registered on 25 September 2017 at Clinical Trials, identifier NCT03290924 .
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.