SynthesisJournal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses
Assessment Tools for Peripheral Neuropathy in Pediatric Oncology: A Systematic Review From the Children's Oncology Group.
Synthesis in Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology Nurses. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Assessment measures for chemotherapy-induced peripheral neuropathy among pediatric oncology patients: an updated systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Approaches to measure paediatric chemotherapy-induced peripheral neurotoxicity: a systematic review.The Lancet. Haematology · 2020Pooled it
- Randomized controlled trial on the effect of 1-hour infusion of vincristine versus push injection on neuropathy in children with cancer (final analysis).Cancer medicine · 2023Trial
- Physical Therapy Surveillance in Children with Acute Lymphoblastic Leukemia: A Quality Improvement Initiative.Pediatric reports · 2026Article
- Article
- Smart exercise in pediatric oncology: enhancing executive functions through cognitively challenging physical activity- a non-randomized controlled trial.BMC cancer · 2025Article
- Investigating fine and gross motor deficits in pediatric patients off therapy for acute lymphoblastic leukemia.Annals of medicine · 2025Article
- A Scoping Review of Chemotherapy-induced Peripheral Neuropathy-Related Gait Abnormalities in Children With Cancer.Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association · 2025Article
- Without ENMG, detecting pediatric vincristine neuropathy is a challenge.Clinical neurophysiology practice · 2024Article
- Performance of the FACT-GOG-Ntx to assess chemotherapy-induced peripheral neuropathy (CIPN) in pediatric high risk Hodgkin lymphoma: report from the Children's Oncology Group AHOD 1331 study.Journal of patient-reported outcomes · 2023Article
- Assessment of proxy-reported responses as predictors of motor and sensory peripheral neuropathy in children with B-lymphoblastic leukemia.Pediatric blood & cancer · 2023Article
- Children's Oncology Group 2023 blueprint: Nursing discipline.Pediatric blood & cancer · 2023Article
- The Battlefield of Chemotherapy in Pediatric Cancers.Cancers · 2023Review
- Article
- Peripheral neuropathy in HIV-infected children attending care and treatment clinic, at Muhimbili National Hospital, Dar es Salaam: a cross sectional study.BMC neurology · 2021Article
- Article
- Autoimmune Ataxia During Maintenance Therapy for Acute Lymphoblastic Leukemia.Child neurology open · 2018Article
- Assessment of Pediatric Chemotherapy-Induced Peripheral Neuropathy Using a New Patient-Reported Outcome Measure: The P-CIN.Journal of pediatric oncology nursing : official journal of the Association of Pediatric Oncology NursesArticle
- Reflections on the Past Decade in Evidence-Based Practice Within the Children's Oncology Group.Journal of pediatric hematology/oncology nursingArticle
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
Peripheral neuropathy is a known side effect of several chemotherapy agents, including vinca alkaloids and platinum-based chemotherapy. Early recognition and monitoring of this side effect is an important role of the pediatric oncology nurse. There are a variety of peripheral neuropathy assessment tools currently in use, but the usefulness of these tools in identifying and grading neuropathy in children varies, and there is currently no standardized tool in place to evaluate peripheral neuropathy in pediatric oncology. A systematic review was performed to identify the peripheral neuropathy assessment tools that best evaluate the early onset and progression of peripheral neuropathy in pediatric patients receiving vincristine. Because of the limited information available in pediatric oncology, this review was extended to any pediatric patient with neuropathy. A total of 8 studies were included in the evidence synthesis. Based on available evidence, the pediatric-modified Total Neuropathy Scale (ped-m TNS) and the Total Neuropathy Score-pediatric version (TNS-PV) are recommended for the assessment of vincristine-induced peripheral neuropathy in children 6 years of age and older. In addition, several studies demonstrated that subjective symptoms alone are not adequate to assess for vincristine-induced peripheral neuropathy. Nursing assessment of peripheral neuropathy should be an integral and regular part of patient care throughout the course of chemotherapy treatment.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.