Evidence map›Paper›PMID 29566285›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2018

Non-Uniform and Absolute Minimal Sampling for High-Throughput Multidimensional NMR Applications.

Dawei Li, Alexandar L Hansen, Lei Bruschweiler-Li, Rafael Brüschweiler

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Elusive Toxin inACS omega · 2021
    Article
  4. Article
  5. Review
  6. International journal of molecular sciences · 2019
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dawei LiCampus Chemical Instrument Center, The Ohio State University, Columbus, Ohio, 43210, USA.
Alexandar L HansenCampus Chemical Instrument Center, The Ohio State University, Columbus, Ohio, 43210, USA.
Lei Bruschweiler-LiCampus Chemical Instrument Center, The Ohio State University, Columbus, Ohio, 43210, USA.
Rafael BrüschweilerCampus Chemical Instrument Center, The Ohio State University, Columbus, Ohio, 43210, USA.ORCID http://orcid.org/0000-0003-3649-4543

Funding

New hybrid methods for the improved and integrated analysis of complex metabolomics mixturesR01GM066041 · NIGMS · OHIO STATE UNIVERSITY · PI BRUSCHWEILER, RAFAEL · 2002 to 2019
$3.3M
NIGMS NIH HHS R01 GM066041
6 · The paper itself

Abstract

Many biomolecular NMR applications can benefit from the faster acquisition of multidimensional NMR data with high resolution and their automated analysis and interpretation. In recent years, a number of non-uniform sampling (NUS) approaches have been introduced for the reconstruction of multidimensional NMR spectra, such as compressed sensing, thereby bypassing traditional Fourier-transform processing. Such approaches are applicable to both biomacromolecules and small molecules and their complex mixtures and can be combined with homonuclear decoupling (pure shift) and covariance processing. For homonuclear 2D TOCSY experiments, absolute minimal sampling (AMS) permits the drastic shortening of measurement times necessary for high-throughput applications for identification and quantification of components in complex biological mixtures in the field of metabolomics. Such TOCSY spectra can be comprehensively represented by graphic theoretical maximal cliques for the identification of entire spin systems and their subsequent query against NMR databases. Integration of these methods in webservers permits the rapid and reliable identification of mixture components. Recent progress is reviewed in this Minireview.

Indexed as

automated spectral analysisbiomolecularmetabolomicsNMR experimentsnuclear magnetic resonance

Identifiers

PMID29566285
PMCPMC6488043

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.