ArticleThe Journal of heredity2018
Allelic Variation in a Single Genomic Region Alters the Microbiome of the Snail Biomphalaria glabrata.
Article in The Journal of heredity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Limited impact of schistosome infection on Biomphalaria glabrata snail microbiomes.Parasites & vectors · 2026Article
- Schistosome species, parasite development, and co-infection combinations determine microbiome dynamics in the snail Biomphalaria glabrata.Animal microbiome · 2025Article
- Organ-specific microbiomes of Biomphalaria snails.Animal microbiome · 2025Article
- Assessing the microbiota of the snail intermediate host of trematodes, Galba truncatula.Parasites & vectors · 2024Article
- Form and Function in the Digenea, with an Emphasis on Host-Parasite and Parasite-Bacteria Interactions.Advances in experimental medicine and biology · 2024Review
- Gut microbiota in parasite-transmitting gastropods.Infectious diseases of poverty · 2023Review
- Host-bacteriome transplants of the schistosome snail host Biomphalaria glabrata reflect species-specific associations.FEMS microbiology ecology · 2023Article
- Host-Associated Bacterial Communities Vary Between Daphnia galeata Genotypes but Not by Host Genetic Distance.Microbial ecology · 2023Article
- Metagenome-Assembled Genomes Reveal Mechanisms of Carbohydrate and Nitrogen Metabolism of Schistosomiasis-Transmitting VectorMicrobiology spectrum · 2022Article
- Molecular characterization of thioester-containing proteins inFrontiers in immunology · 2022Article
- Experimental Infection of theMicroorganisms · 2021Article
- New Insights Into Biomphalysin Gene Family Diversification in the Vector SnailFrontiers in immunology · 2021Article
- The hemolymph of Biomphalaria snail vectors of schistosomiasis supports a diverse microbiome.Environmental microbiology · 2020Article
- Clusters of polymorphic transmembrane genes control resistance to schistosomes in snail vectors.eLife · 2020Article
- Article
- Allelic variation in a single genomic region alters the hemolymph proteome in the snail Biomphalaria glabrata.Fish & shellfish immunology · 2019Article
- Schistosomiasis Vector Snails and Their Microbiota Display a Phylosymbiosis Pattern.Frontiers in microbiology · 2019Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Freshwater snails are the intermediate hosts for numerous parasitic worms which can have negative consequences for human health and agriculture. Understanding the transmission of these diseases requires a more complete characterization of the immunobiology of snail hosts. This includes the characterization of its microbiome and genetic factors which may interact with this important commensal community. Allelic variation in the Guadeloupe resistance complex (GRC) genomic region of Guadeloupean Biomphalaria glabrata influences their susceptibility to schistosome infection and may have other roles in the snail immune response. In the present study, we examined whether a snail's GRC genotype has a role in shaping the bacterial diversity and composition present on or in whole snails. We show that the GRC haplotype, including the resistant genotype, has a significant effect on the diversity of bacterial species present in or on whole snails, including the relative abundances of Gemmatimonas aurantiaca and Micavibrio aeruginosavorus. These findings support the hypothesis that the GRC region is likely involved in pathways that can modify the microbial community of these snails and may have more immune roles in B. glabrata than originally believed. This is also one of few examples in which allelic variation at a particular locus has been shown to affect the microbiome in any species.
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