Evidence map›Paper›PMID 29566093›Full record

ArticlePloS one2018

Patterns of sensitization to inhalant and food allergens among pediatric patients from the Moscow region (Russian Federation).

Sergei Voloshin, Olga Smoldovskaya, Guzel Feyzkhanova, Alla Arefieva, Lyudmila Pavlushkina, Tatiana Filatova, Veronika Butvilovskaya, Marina Filippova, Yuri Lysov, Sergey Shcherbo and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Sergei VoloshinEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Olga SmoldovskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.ORCID 0000-0002-9947-4446
Guzel FeyzkhanovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Alla ArefievaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Lyudmila PavlushkinaFilatov Moscow City Pediatric Clinic No. 13, Moscow, Russia.
Tatiana FilatovaFilatov Moscow City Pediatric Clinic No. 13, Moscow, Russia.
Veronika ButvilovskayaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Marina FilippovaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Yuri LysovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Sergey ShcherboFilatov Moscow City Pediatric Clinic No. 13, Moscow, Russia.
Alexander MakarovEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Alla RubinaEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Alexander ZasedatelevEngelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
Engelhardt Institute of Molecular Biology · RUCity Clinical Hospital No15 named. O. M. Filatova · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The immunological profiles of human specific IgE (sIgE) and specific IgG4 (sIgG4) vary by genetic predisposition, living conditions in different geographical locations and patient's age. The aim of our study was to analyze sIgE and sIgG4 patterns and their age-dependent changes in patients from the Moscow region. For identifying sIgE and sIgG4 profiles the blood samples from 513 patients aged 6 months to 17 years who were showing symptoms of allergic diseases were analyzed using microarrays containing 31 allergens. The highest sIgE prevalence was observed for birch pollen (32%) among pollen allergens, cat dander (24%) among indoor allergens, and egg whites (21%) among food allergens. The most common sIgG4 response was developed toward egg whites (80% of patients). Age-related elevation was identified for patients with increased sIgE to pollen allergens and indoor allergens (cat or dog dander and house dust mites). For each allergen, the proportion of cases with significant levels of sIgG4 appeared to increase with patients' age. The data on allergen-specific sIgE and sIgG4 prevalence show both general trends and some local special aspects that are indicative for the Moscow region. This information should be useful in terms of epidemiology of allergic diseases.

Indexed as

AdolescentAllergensBronchial Provocation TestsChildChild, PreschoolFemaleFood HypersensitivityHumansInfantInfant, NewbornMaleMicroarray AnalysisMoscowRespiratory HypersensitivityRussiaAllergens

Identifiers

PMID29566093
PMCPMC5864043
OpenAlexW2791438427

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.