ArticlePloS one2018
Paper-based sensors for rapid detection of virulence factor produced by Pseudomonas aeruginosa.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Emerging advances in biosensor technologies for quorum sensing signal molecules.Analytical and bioanalytical chemistry · 2025Review
- Miniaturized Devices for Isothermal Amplification and Photometric Quantification of Pseudomonas Aeruginosa.IEEE open journal of engineering in medicine and biology · 2025Article
- Article
- Advances in paper-based electrochemical immunosensors: review of fabrication strategies and biomedical applications.Royal Society open science · 2023Review
- Article
- A paper biosensor for overcoming matrix effects interfering with the detection of sputum pyocyanin with competitive immunoassays.Mikrochimica acta · 2023Article
- Two-Dimensional Non-Carbon Materials-Based Electrochemical Printed Sensors: An Updated Review.Sensors (Basel, Switzerland) · 2022Review
- Research Progress and Future Trends of Microfluidic Paper-Based Analytical Devices in In-Vitro Diagnosis.Biosensors · 2022Review
- Redox cycling-based detection of phenazine metabolites secreted from Pseudomonas aeruginosa in nanopore electrode arrays.The Analyst · 2021Article
- Pathogen detection with electrochemical biosensors: Advantages, challenges and future perspectives.Journal of electroanalytical chemistry (Lausanne, Switzerland) · 2021Review
- Diagnosis and Stratification ofFrontiers in cellular and infection microbiology · 2021Article
- Article
- Electrochemical Detection of Pyocyanin as a Biomarker forSensors (Basel, Switzerland) · 2020Review
- Phenazines as potential biomarkers of Pseudomonas aeruginosa infections: synthesis regulation, pathogenesis and analytical methods for their detection.Analytical and bioanalytical chemistry · 2020Review
- Screen-Printed Electrodes: Promising Paper and Wearable Transducers for (Bio)Sensing.Biosensors · 2020Review
- Article
- Liquid Crystal Emulsions That Intercept and Report on Bacterial Quorum Sensing.ACS applied materials & interfaces · 2020Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pyocyanin is a toxin produced by Pseudomonas aeruginosa. Here we describe a novel paper-based electrochemical sensor for pyocyanin detection, manufactured with a simple and inexpensive approach based on electrode printing on paper. The resulting sensors constitute an effective electrochemical method to quantify pyocyanin in bacterial cultures without the conventional time consuming pretreatment of the samples. The electrochemical properties of the paper-based sensors were evaluated by ferri/ferrocyanide as a redox mediator, and showed reliable sensing performance. The paper-based sensors readily allow for the determination of pyocyanin in bacterial cultures with high reproducibility, achieving a limit of detection of 95 nM and a sensitivity of 4.30 μA/μM in standard culture media. Compared to the similar commercial ceramic based sensors, it is a 2.3-fold enhanced performance. The simple in-house fabrication of sensors for pyocyanin quantification allows researchers to understand in vitro adaptation of P. aeruginosa infections via rapid screenings of bacterial cultures that otherwise are expensive and time-consuming.
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Registered trials
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