Evidence map›Paper›PMID 29566017›Full record

ArticlePloS one2018

Most women living with HIV can deliver vaginally-National data from Finland 1993-2013.

Inka Aho, Marja Kaijomaa, Pia Kivelä, Heljä-Marja Surcel, Jussi Sutinen, Oskari Heikinheimo, with the FINHIVPREG Study team

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Inka AhoDepartment of Infectious diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.ORCID 0000-0002-0281-8485
Marja KaijomaaDepartment of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Pia KiveläDepartment of Infectious diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Heljä-Marja SurcelNational Institute of Health and Welfare, Oulu and Faculty of Medicine, University of Oulu, Oulu, Finland.
Jussi SutinenDepartment of Infectious diseases, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Oskari HeikinheimoDepartment of Obstetrics and Gynecology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
with the FINHIVPREG Study team

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVaginal delivery has been recommended for more than ten years for women living with HIV (WLWH) with good virological control. However, in Europe most WLWH still deliver by cesarean section (CS). Our aim was to assess the rate of vaginal delivery and the indications for CS in WLWH over 20 years in a setting of low overall CS rate. MATERIALS AND

methodsThis was a retrospective study of all WLWH delivering in Finland 1993-2013. We identified the women by combining national health registers and extracted data from patient files.

resultsThe study comprised 212 women with 290 deliveries. Over 35% of the women delivered several children during the study years. During 2000-2013, with consistent viral load monitoring, 80.0% showed HIV viral loads <50 copies/mL in the last measurement preceding the delivery. Altogether 74.5% of all WLWH delivered vaginally and the rate of both elective CS and emergency CS was 12.8% each. For most CSs (63.5%) the indication was obstetrical, for 28.4% it was avoiding HIV transmission and for 0.7% it was mother's request. In hospitals with less than ten HIV-related deliveries during the study period, the rate of elective CS was higher than in more experienced hospitals (22.7% versus 10.6% [p = 0.024]). No perinatal HIV transmissions occurred.

conclusionsMost WLWH can achieve good virological control and deliver vaginally. This will help them to maintain their future child bearing potential and reduce CS-related morbidity.

Indexed as

AdultAnti-HIV AgentsCesarean SectionDelivery, ObstetricFemaleFinlandHIVHIV InfectionsHumansInfant, NewbornInfectious Disease Transmission, VerticalPregnancyPregnancy Complications, InfectiousRegistriesRetrospective StudiesViral LoadAnti-HIV Agents

Identifiers

PMID29566017
PMCPMC5864005

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.