ArticlePloS one2018
Zoonotic Babesia microti in the northeastern U.S.: Evidence for the expansion of a specific parasite lineage.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
21 citing papers in PubMed.
- Coinfection ecology and pathogen emergence in aApplied and environmental microbiology · 2026Article
- Coinfection Ecology and Pathogen Emergence in amedRxiv : the preprint server for health sciences · 2025Article
- Design and screening of novel molecular compounds targeting lactate dehydrogenase of Babesia microti.Parasites & vectors · 2025Article
- Article
- Transcriptional variation in Babesia gibsoni (Wuhan isolate) between in vivo and in vitro cultures in blood stage.Parasites & vectors · 2023Article
- EVIDENCE OF PROTOZOAN AND BACTERIAL INFECTION AND CO-INFECTION AND PARTIAL BLOOD FEEDING IN THE INVASIVE TICK HAEMAPHYSALIS LONGICORNIS IN PENNSYLVANIA.The Journal of parasitology · 2023Article
- Detection of multiple tick-borne pathogens inCurrent research in parasitology & vector-borne diseases · 2023Article
- The impact of ABO and RhD blood types on Babesia microti infection.PLoS neglected tropical diseases · 2023Article
- Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood.Frontiers in microbiology · 2022Article
- Human Babesiosis in Europe.Pathogens (Basel, Switzerland) · 2021Review
- Semicentennial of Human Babesiosis, Nantucket Island.Pathogens (Basel, Switzerland) · 2021Review
- Vertical Transmission: A Vector-Independent Transmission Pathway of Babesia microti in the Natural Reservoir Host Peromyscus leucopus.The Journal of infectious diseases · 2021Article
- Impact of Babesia microti infection on the initiation and course of pregnancy in BALB/c mice.Parasites & vectors · 2021Article
- Review
- The Centers for Disease Control and Prevention and State Health Departments should include Blood-Type Variables in their Babesiosis Case Reports.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2020Article
- Prevalence of protozoan parasites in small and medium mammals in Texas, USA.International journal for parasitology. Parasites and wildlife · 2020Article
- Polymicrobial Nature of Tick-Borne Diseases.mBio · 2019Article
- Development of a SNP barcode to genotype Babesia microti infections.PLoS neglected tropical diseases · 2019Article
- Increasing Babesiosis in Southeastern Pennsylvania, 2008-2017.Open forum infectious diseases · 2019Article
- Precision medicine: retrospective chart review and data analysis of 200 patients on dapsone combination therapy for chronic Lyme disease/post-treatment Lyme disease syndrome: part 1.International journal of general medicine · 2019Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The recent range expansion of human babesiosis in the northeastern United States, once found only in restricted coastal sites, is not well understood. This study sought to utilize a large number of samples to examine the population structure of the parasites on a fine scale to provide insights into the mode of emergence across the region. 228 B. microti samples collected in endemic northeastern U.S. sites were genotyped using published Variable number tandem repeat (VNTR) markers. The genetic diversity and population structure were analysed on a geographic scale using Phyloviz and TESS, programs that utilize two different methods to identify population membership without predefined population data. Three distinct populations were detected in northeastern US, each dominated by a single ancestral type. In contrast to the limited range of the Nantucket and Cape Cod populations, the mainland population dominated from New Jersey eastward to Boston. Ancestral populations of B. microti were sufficiently isolated to differentiate into distinct populations. Despite this, a single population was detected across a large geographic area of the northeast that historically had at least 3 distinct foci of transmission, central New Jersey, Long Island and southeastern Connecticut. We conclude that a single B. microti genotype has expanded across the northeastern U.S. The biological attributes associated with this parasite genotype that have contributed to such a selective sweep remain to be identified.
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