Observational studyCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2018
Impact of frailty on outcomes after discharge in older surgical patients: a prospective cohort study.
Observational study in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02233153 (Elder-friendly Approaches to the Surgical Environment - Implementation of an Elder Friendly Surgical Unit), which is not on this map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Elder-friendly Approaches to the Surgical Environment - Implementation of an Elder Friendly Surgical Unit
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Impact of Frailty on Activities of Daily Living in Hospitalized Older Adults: A Systematic Review and Meta-Analysis.Geriatrics & gerontology international · 2026Pooled it
- Pooled it
- The Association Between the Clinical Frailty Scale and Adverse Health Outcomes in Older Adults in Acute Clinical Settings - A Systematic Review of the Literature.Clinical interventions in aging · 2023Pooled it
- Frailty and Emergency Surgery: Results of a Systematic Review and Meta-Analysis.Frontiers in medicine · 2022Pooled it
- Frailty Increases the Risk and Frequency of Lower Respiratory Tract Infections in Older Adults: A Multicenter Prospective Cohort Study.Open forum infectious diseases · 2026Article
- The Association of Frailty With Post-Hospital Discharge Location and Health Outcomes.Journal of the American Geriatrics Society · 2025Article
- Review
- Frailty and body composition predict adverse outcomes after emergency general surgery admission: a multicentre observational cohort study.Annals of the Royal College of Surgeons of England · 2025Observational
- Emergency Colon Resection in the Geriatric Population: the Modified Frailty Index as a Risk Factor of Early Mortality.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2023Article
- Influence of interdisciplinary frailty screening on perioperative complication rates in elderly ovarian cancer patients: results of a retrospective observational study.Archives of gynecology and obstetrics · 2023Observational
- Surgeon-reported Factors Influencing Adoption of Quality Standards for Goal-concordant Care in Patients With Advanced Cancer: A Qualitative Study.Annals of surgery · 2023Article
- Frailty assessment tools predict perioperative outcome in elderly patients with endometrial cancer better than age or BMI alone: a retrospective observational cohort study.Journal of cancer research and clinical oncology · 2023Observational
- Preoperative frailty assessment could be a predictive factor for the prognosis of elderly patients undergoing coronary artery bypass grafting: a retrospective case-control study.BMC anesthesiology · 2023Article
- Associations of intrinsic capacity, fall risk and frailty in old inpatients.Frontiers in public health · 2023Observational
- Enhanced Telehealth Home-Monitoring Intervention for Vulnerable and Frail Patients after Cardiac Surgery (THE-FACS Pilot Intervention Study).BMC geriatrics · 2022Article
- Frailty as a Predictor of Hospitalization and Low Quality of Life in Geriatric Patients at an Internal Medicine Outpatient Clinic: A Cross-Sectional Study.Geriatrics (Basel, Switzerland) · 2022Article
- Frailty assessment tools for use by surgeons when evaluating older adults prior to surgery: a scoping review protocol.BMJ open · 2022Article
- Heath status, frailty, and multimorbidity in patients with emergency general surgery conditions.Surgery · 2022Article
- Article
- Impact of preoperative laboratory frailty index on mortality and clinical outcomes in older surgical patients with cancer.Scientific reports · 2022Article
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFrailty is a state of vulnerability to diverse stressors. We assessed the impact of frailty on outcomes after discharge in older surgical patients.
methodsWe prospectively followed patients 65 years of age or older who underwent emergency abdominal surgery at either of 2 tertiary care centres and who needed assistance with fewer than 3 activities of daily living. Preadmission frailty was defined according to the Canadian Study of Health and Aging Clinical Frailty Scale as "well" (score 1 or 2), "vulnerable" (score 3 or 4) or "frail" (score 5 or 6). We assessed composite end points of 30-day and 6-month all-cause readmission or death by multivariable logistic regression.
resultsOf 308 patients (median age 75 [range 65-94] yr, median Clinical Frailty Score 3 [range 1-6]), 168 (54.5%) were classified as vulnerable and 68 (22.1%) as frail. Ten (4.2%) of those classified as vulnerable or frail received a geriatric consultation. At 30 days after discharge, the proportions of patients who were readmitted or had died were greater among vulnerable patients (
interpretationVulnerability and frailty were prevalent in older patients undergoing surgery and unlikely to trigger specialized geriatric assessment, yet remained independently associated with greater risk of readmission for as long as 6 months after discharge. Therefore, the degree of frailty has important prognostic value for readmission. TRIAL REGISTRATION FOR PRIMARY STUDY: ClinicalTrials.gov, no. NCT02233153.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.