Evidence map›Paper›PMID 29564738›Full record

ArticleJournal of assisted reproduction and genetics2018

Platelet-rich plasma therapy and reproductive medicine.

Adriana Bos-Mikich, Ricardo de Oliveira, Nilo Frantz

2 registry-linked trialsAbstract readEditorial
In one paragraph

Article in Journal of assisted reproduction and genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 68 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04797377 nacompletednot on this mapstarted 2021, after this paper: background citation

Effects of Autologous Intraovarian Platelet Rich Plasma in Women With Poor Ovarian Response

TypeinterventionalSponsorNadezhda Women's Health HospitalRan2021 to 2021Enrolled66ConditionsPoor Ovarian ReserveArmsAutologous ovarian PRP injection
NCT06261658 narecruitingnot on this mapstarted 2024, after this paper: background citation

Improving the Quality of Cryopreserved Ovarian Tissue Reimplantation Using Platelet-enriched Autologous Plasma

TypeinterventionalSponsorIRCCS Azienda Ospedaliero-Universitaria di BolognaRan2024 to 2033Enrolled45ConditionsCryopreservation, Ovary Injury, Infertility, Female, Menopause Ovarian FailureArmsCryopreserved Ovarian Tissue Reimplantation
3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  4. Autologous platelet-rich plasma for assisted reproduction.The Cochrane database of systematic reviews · 2024
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  8. Platelet-rich plasma versus granulocyte colony-stimulating factor in addressing recurrent implantation failure: A randomized, double-blind clinical trial.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2026
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8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adriana Bos-MikichFederal University of Rio Grande do Sul, Porto Alegre, Brazil. Adriana.bosmikich@gmail.com.ORCID http://orcid.org/0000-0001-5704-1936
Ricardo de OliveiraRDO Medical Diagnosis, São Paulo, Brazil.
Nilo FrantzNilo Frantz Human Reproduction Center, Porto Alegre, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reports on clinical uses of platelet-rich plasma (PRP) have dramatically increased in the last decade. Indications for PRP therapy range from muscle and skeletal injuries to hair re-growth. More recently evidences have shown its positive effects in promoting endometrial and follicular growth and gestation in assisted reproduction cycles. We discuss the putative role of PRP on endometrial receptivity, with a brief history of its applications in research and clinical therapies. Despite its widespread uses in medicine, the mechanisms through which PRP exerts its regenerative effects are only postulated, not based on scientific data. There is an unmet need for advanced research to corroborate present findings in the clinical scenario.

Indexed as

Platelet-Rich PlasmaEndometriumFemaleHumansPregnancyReproductive Medicine

Identifiers

PMID29564738
PMCPMC5984895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.