ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2018
Documenting an epidemic of suffering: low health-related quality of life among transgender youth.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
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Who cites it
6 citing papers in PubMed, 21 citations in OpenAlex.
- Emotional quality-of-life after chest masculinizing surgery among transgender persons aged under versus over 18 years: a comparative observational study.Journal of patient-reported outcomes · 2026Observational
- "Being here, you could actually be yourself": Trans and gender expansive youth's experiences of affirmation within LGBTQ+ community-based organizations.Psychological services · 2026Article
- "[He] can be supportive, but at times I feel he is ashamed of me": Understanding the relationship between parental support and quality of life amongst trans and gender diverse youth in the UK.International journal of transgender health · 2024Article
- Assessment of Quality of Life of Transgender and Gender-Diverse Children and Adolescents in Melbourne, Australia, 2017-2020.JAMA network open · 2023Article
- Health-related quality of life among transgender and gender expansive youth at a rural gender wellness clinic.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020Article
- Brazilian transgender children and adolescents: Attributes associated with quality of life.Revista latino-americana de enfermagem · 2020Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo quantify HRQOL of TGN patients using the PedsQL 4.0 generic core scales, and to compare reported HRQOL of TGN adolescents with published data from comparison populations.
methodsTransgender children and adolescents (N = 142; 68% natal females) ages 6-23 years (M = 15.9, SD = 3.7) attending an outpatient clinic for TGN care at an academic pediatric hospital and caregivers of children and adolescents (N = 95) completed the PedsQL 4.0 generic core scales. Scores were compared with published scores for healthy adolescents and adolescents with 10 chronic diseases.
resultsTGN youth reported significantly lower overall HRQOL (more than twice the clinically meaningful difference) compared to youth without chronic disease. Total self-reported TGN HRQOL (M(SD), 65.72(17.40)) was lower than all chronic disease comparison groups except for rheumatology and cerebral palsy. TGN youth reported physical functioning (M(SD), 75.33(22.87)) lower than or similar to chronically ill comparisons, but higher than rheumatology and cerebral palsy groups. Psychosocial functioning (M(SD), 59.87(17.83)) was lower than all comparison samples and similar to youth with cerebral palsy. Results were similar for parent proxy-reports of TGN youth HRQOL (LS means: 68.75; 95% CI 65.87-71.61 vs 66.16; 95% CI 62.87-69.45; p = 0.12).
conclusionsTGN youth reported low HRQOL across all domains; most were significantly lower than healthy peers or peers with chronic diseases. Clinicians should understand the magnitude of TGN youth's low HRQOL and offer them and their caregivers resources to maximize their ability to achieve their full potential for healthy and productive lives.
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Registered trials
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