Evidence map›Paper›PMID 29564664›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018

Long-term outcomes following percutaneous left atrial appendage closure in patients with atrial fibrillation and contraindications to anticoagulation.

Ander Regueiro, Ignacio Cruz-Gonzalez, Armando Bethencourt, Luis Nombela-Franco, Jean Champagne, Luis Asmarats, Pilar Jiménez-Quevedo, Tania Rodriguez-Gabella, Juan Carlos Rama-Merchan, Rishi Puri and 2 more

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Women and atrial fibrillation.Journal of cardiovascular electrophysiology · 2021
    Review
  6. Article
  7. Review
  8. Left Atrial Appendage Anatomy: Implications for Endocardial Catheter-based Device Closure.The Journal of innovations in cardiac rhythm management · 2020
    Review
  9. Article
  10. Observational
  11. Atrial fibrillation in the elderly.Journal of geriatric cardiology : JGC · 2019
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ander RegueiroQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada.
Ignacio Cruz-GonzalezHospital Universitario de Salamanca, Salamanca, Spain.
Armando BethencourtHospital Universitario Son Espases, Palma de Mallorca, Spain.
Luis Nombela-FrancoInstituo Cardiovascular, Hospital Clínico Universitario San Carlos, Instituto de Investigacion Sanitaria, Madrid, Spain.
Jean ChampagneQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada.
Luis AsmaratsQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada.
Pilar Jiménez-QuevedoInstituo Cardiovascular, Hospital Clínico Universitario San Carlos, Instituto de Investigacion Sanitaria, Madrid, Spain.
Tania Rodriguez-GabellaQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada.
Juan Carlos Rama-MerchanHospital Universitario de Salamanca, Salamanca, Spain.
Rishi PuriQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada.
Gilles O'HaraQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada.
Josep Rodés-CabauQuebec Heart & Lung Institute, Laval University, 2725 Chemin Ste-Foy, Quebec City, Quebec, G1V 4GS, Canada. josep.rodes@criucpq.ulaval.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate the late clinical outcomes of percutaneous LAA closure in patients with atrial fibrillation (AF) and contraindication to oral anticoagulation.

methodsConsecutive AF patients with contraindications to oral anticoagulation who underwent successful LAA closure between December 2008 and March 2013 at four centers were included.

resultsA total of 101 patients (median age 76 [IQR 69-80] years, 48% women, mean CHA

conclusionsPercutaneous LAA closure is safe and effective in the long term in patients with AF with contraindications to anticoagulation. However, a high long-term mortality rate was observed in this high-risk population. Comprehensive patient assessment prior to undergoing LAA closure should identify patients in whose comorbidities limit their overall prognosis.

Indexed as

Patient SafetyAdministration, OralAgedAged, 80 and overAge FactorsAnticoagulantsAtrial AppendageAtrial FibrillationCardiac CatheterizationCohort StudiesContraindicationsFemaleHumansKaplan-Meier EstimateMalePatient SelectionAnticoagulantsBleedingLeft atrial appendage closureStroke

Identifiers

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.