Evidence map›Paper›PMID 29564622›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2018

Impact of reconceptualization response shift on rating of quality of life over time among people with advanced cancer.

Ala' S Aburub, B Gagnon, S Ahmed, A M Rodríguez, Nancy E Mayo

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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Integration of early palliative care in cancer treatment: a meta-analysis of 39 randomized controlled trials on clinical outcomes and management optimization.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Impact of response shift on change in patient-reported outcomes: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Pooled it
  3. Response shift results of quantitative research using patient-reported outcome measures: a descriptive systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024
    Pooled it
  4. Pooled it
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  7. Using Patient-Reported Outcome Measures to Identify Mobility Limitation in Incurable Cancer.Archives of rehabilitation research and clinical translation · 2026
    Article
  8. Implications of the syntheses on definition, theory, and methods conducted by the Response Shift - in Sync Working Group.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
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  10. Review
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  13. Appraisal as a unifying theory of response shift: continuing the conversation.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ala' S AburubSchool of Physical and Occupational Therapy, Division of Clinical Epidemiology, Royal Victoria Hospital Site, McGill University, Ross Pavilion R4.29, 687, Pine Ave W., Montreal, QC, H3A 1A1, Canada. ala.aburub@mail.mcgill.ca.
B GagnonDépartement de médecine familiale et de médecine d'urgence, Centre de Recherche sur le Cancer, Centre de recherche du CHU de Québec, Universite Laval, 9 rue McMahon, Québec, QC, G1R 2J6, Canada.
S AhmedSchool of Physical and Occupation Therapy, Division of Clinical Epidemiology, Centre de recherche interdisciplinaire réadaptation (CRIR) constance Lethbridge rehabilitaion Center, McGill University Health Centre, 3654 prom Sir-William-Osler, Montreal, QC, H3G 1Y5, Canada.
A M RodríguezSchool of Rehabilitation Sciences, McGill University, 3654 Prom Sir-William-Osler, Montreal, QC, H3G 1Y5, Canada.
Nancy E MayoDivision of Clinical Epidemiology, Royal Victoria Hospital Site, McGill University Health Center, Ross Pavilion R4.29, Montreal, QC, H3A 1A1, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople with cancer may experience change in what constitutes quality of life (QOL) over time as a result of the cancer progression (true change) or adaptation to the experience, considered as a response shift phenomenon. As individualized measures are ideally suited to explore response shift, this study aimed to estimate the extent to which reconceptualization response shift occurred over time in a cancer population and the impact of this response shift on estimates of change on QOL measures.

methodsNinety-seven people with advanced cancer completed the study measures including the Patient-Generated Index (PGI) at diagnosis (T0) and 1 year later (T1). The response shift indicator was the change in the number of areas nominated (range - 4 to + 3). Multivariate linear regression was used to estimate the effect of changing areas on change in the PGI score, single indicators of global QOL, and the EQ-5D

resultsApproximately 72% of people in this sample either added or dropped areas over time. People who dropped more than two areas had higher PGI scores at T1 than T0 while people who added areas showed low PGI score.

conclusionThe results are consistent with the PGI framework as areas nominated tend to focus on negative aspects of QOL.

Indexed as

Patient Reported Outcome MeasuresAgedFemaleHumansMaleMiddle AgedNeoplasmsQuality of LifeSurveys and QuestionnairesIndividualized measuresPatient-Generated Index (PGI)Quality of lifeReconceptualizationResponse shift

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.