Evidence map›Paper›PMID 29564490›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2018

Use of FET PET in glioblastoma patients undergoing neurooncological treatment including tumour-treating fields: initial experience.

Garry Ceccon, Lazaros Lazaridis, Gabriele Stoffels, Marion Rapp, Manuel Weber, Tobias Blau, Phillip Lohmann, Sied Kebir, Ken Herrmann, Gereon R Fink and 3 more

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. [European journal of nuclear medicine and molecular imaging · 2023
    Article
  4. Review
  5. Nuclear Medicine Imaging Procedures in Oncology.Methods in molecular biology (Clifton, N.J.) · 2021
    Article
  6. Article
  7. Article
  8. Review
  9. Prognostic Value of O-(2-[Molecular imaging and biology · 2019
    Article
  10. Tumor treating fields in the management of Glioblastoma: opportunities for advanced imaging.Cancer imaging : the official publication of the International Cancer Imaging Society · 2019
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Garry CecconDepartment of Neurology, University Hospital Cologne, Josef-Stelzmann St. 9, 50937, Cologne, Germany.
Lazaros LazaridisDivision of Clinical Neuro-Oncology, Department of Neurology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Gabriele StoffelsInstitute of Neuroscience and Medicine (INM-3,-4), Forschungszentrum Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Marion RappDepartment of Neurosurgery, University of Düsseldorf, Düsseldorf, Germany.
Manuel WeberDepartment of Nuclear Medicine, University of Essen, Essen, Germany.
Tobias BlauDepartment of Neuropathology, University of Essen, Essen, Germany.
Phillip LohmannInstitute of Neuroscience and Medicine (INM-3,-4), Forschungszentrum Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Sied KebirDivision of Clinical Neuro-Oncology, Department of Neurology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Ken HerrmannDepartment of Nuclear Medicine, University of Essen, Essen, Germany.
Gereon R FinkDepartment of Neurology, University Hospital Cologne, Josef-Stelzmann St. 9, 50937, Cologne, Germany.
Karl-Josef LangenInstitute of Neuroscience and Medicine (INM-3,-4), Forschungszentrum Juelich, Leo-Brandt-St. 5, 52425, Juelich, Germany.
Martin GlasDivision of Clinical Neuro-Oncology, Department of Neurology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Norbert GalldiksDepartment of Neurology, University Hospital Cologne, Josef-Stelzmann St. 9, 50937, Cologne, Germany. n.galldiks@fz-juelich.de.ORCID http://orcid.org/0000-0002-2485-1796

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe present our first clinical experience with O-(2-

methodsWe retrospectively assessed 12 patients (mean age 51 ± 12 years, range 33-72 years) with high-grade glioma (11 glioblastomas, 1 gliosarcoma) in whom the treatment regimen included TTFields and who had undergone FET PET scans for differentiation of tumour progression from treatment-related changes. Mean and maximum tumour-to-brain ratios (TBR

resultsIn all nine patients with confirmed tumour progression, the corresponding FET PET showed increased uptake (TBR

conclusionFET PET may add valuable information in monitoring therapy in individual patients with high-grade glioma undergoing neurooncological treatment including TTFields.

Indexed as

Positron-Emission TomographyAdultAgedBrain NeoplasmsFemaleGlioblastomaGliomaHumansMagnetic Resonance ImagingMaleMiddle AgedRadiopharmaceuticalsRetrospective StudiesTyrosineRadiopharmaceuticalsTyrosineAmino acid PETGliomaTreatment-related changesTTFieldsTumour progression

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.