Evidence map›Paper›PMID 29564469›Full record

ArticleDer Nervenarzt2019

Pharmacological treatment for schizoaffective disorder : A comparison with schizophrenia and bipolar disorder.

H-J Assion, A Schweppe, H Reinbold, U Frommberger

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Der Nervenarzt, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

H-J AssionLWL-Klinik Dortmund, Marsbruchstr. 179, 44287, Dortmund, Germany. hans-joerg.assion@lwl.org.
A SchweppeTagesklinik des gpz Detmold, Hindenburgstr. 1, 32791, Lage, Germany.
H ReinboldLWL-Klinik Dortmund, Marsbruchstr. 179, 44287, Dortmund, Germany.
U FrommbergerPsychiatry, Psychosomatic Medicine and Psychotherapy, Klinik an der Lindenhöhe, Bertha-von-Suttner-Str. 1, 77654, Offenburg, Germany.
Klinikum Dortmund · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBipolar disorder and schizophrenia are severe mental illnesses, each with a prevalence of approximately 1-2% in the general population. There is considerable controversy about differentiating schizophrenia from schizoaffective or bipolar disorder owing to many similarities in psychopathology, progression, and biological factors. The aim of this study was to identify similarities and differences in the pharmacological treatment of these disorders by comparing the prescription patterns.

methodIn this retrospective, explorative study we analyzed the prescribed medication of 300 patients with bipolar, schizophrenic, or schizoaffective disorders from data obtained from ten German adult psychiatric clinics of the LWL ("Landschaftsverband Westfalen-Lippe") psychiatric network.

resultsOnly 21.8% of patients analyzed were consistently compliant in taking their medication before hospitalization. Polypharmacy was applied in 75.6% of cases, whereby 2.27 psychopharmacological agents were prescribed at discharge. Briefly, we observed greater similarity between prescription patterns associated with bipolar and schizoaffective disorders than with schizophrenia prescription patterns.

conclusionPolypharmacy tends to be more the rule than the exception, especially when patients present with affective psychotic features. Bipolar and schizoaffective disorders cannot be differentiated according to their prescription patterns.

Indexed as

Bipolar DisorderPsychotic DisordersSchizophreniaAdultFemaleGermanyHumansMaleMiddle AgedPolypharmacyRetrospective StudiesAntidepressantsAntipsychoticsLithiumPolypharmacyPsychopharmacology

Identifiers

PMID29564469
OpenAlexW2789532466

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.