ArticleEJNMMI radiopharmacy and chemistry2017
Automation of the Radiosynthesis of Six Different
Article in EJNMMI radiopharmacy and chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer · 2026Review
- Dual-Tracer Imaging on a Long-Axial-Field-of-View PET: A Proof-of-Principle Study with [Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025Article
- Reproducibility and repeatability of 18F-(2S, 4R)-4-fluoroglutamine PET imaging in preclinical oncology models.PloS one · 2025Article
- Preclinical evaluation of the novel [European journal of nuclear medicine and molecular imaging · 2024Article
- Development and application of a fully automatic multi-function cassette module Mortenon M1 for radiopharmaceutical synthesis.Annals of nuclear medicine · 2024Article
- First GPR119 PET Imaging Ligand: Synthesis, Radiochemistry, and Preliminary Evaluations.Journal of medicinal chemistry · 2023Article
- [Scientific reports · 2023Article
- Pilot Study: PARP1 Imaging in Advanced Prostate Cancer.Molecular imaging and biology · 2022Article
- First-in-Human PET Imaging and Estimated Radiation Dosimetry of l-[5-Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022Article
- Method to Development of PET Radiopharmaceutical for Cancer Imaging.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Robust and Facile Automated Radiosynthesis of [Molecular imaging and biology · 2021Article
- Kinetic Modeling ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2021Article
- Underutilisation of nuclear medicine scans at a regional hospital in Nigeria: need for implementation research.Ecancermedicalscience · 2020Article
- 3-Bioorganic & medicinal chemistry · 2019Article
- 3D-printed automation for optimized PET radiochemistry.Science advances · 2019Article
- Initial biological evaluations ofEJNMMI research · 2019Article
- Cell-Proliferation Imaging for Monitoring Response to CDK4/6 Inhibition Combined with Endocrine-Therapy in Breast Cancer: Comparison of [Clinical cancer research : an official journal of the American Association for Cancer Research · 2019Article
- Automated synthesis of [EJNMMI radiopharmacy and chemistry · 2019Article
- Erratum: Publisher Correction toEJNMMI radiopharmacy and chemistry · 2018Article
- The Molecular Industrial Revolution: Automated Synthesis of Small Molecules.Angewandte Chemie (International ed. in English) · 2018Review
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFast implementation of positron emission tomography (PET) into clinical and preclinical studies highly demands automated synthesis for the preparation of PET radiopharmaceuticals in a safe and reproducible manner. The aim of this study was to develop automated synthesis methods for these six
resultsThe development of automated syntheses with varying complexity was accomplished including HPLC purification, SPE procedures and final formulation with sterile filtration. The six radiopharmaceuticals were obtained in high yield and high specific activity with full automation on the AllinOne synthesis module under current good manufacturing practice (cGMP) guidelines.
conclusionThe study demonstrates the versatility of this synthesis module for the preparation of a wide variety of
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