Evidence map›Paper›PMID 29564332›Full record

ArticleFrontiers in surgery2018

Occurrence of Occult Malignancies in Reduction Mammoplasties.

Matthias Waldner, Holger J Klein, Walter Künzi, Merlin Guggenheim, Jan A Plock, Pietro Giovanoli

Abstract read
In one paragraph

Article in Frontiers in surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Safe Reproducible Breast Reduction.Plastic and reconstructive surgery. Global open · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Matthias WaldnerDivision of Plastic Surgery and Hand Surgery, Universitäts Spital Zürich, Zurich, Switzerland.
Holger J KleinDivision of Plastic Surgery and Hand Surgery, Universitäts Spital Zürich, Zurich, Switzerland.
Walter KünziEuro-Policlinic Switzerland, Zurich, Switzerland.
Merlin GuggenheimSwissparc Zürich, Zurich, Switzerland.
Jan A PlockDivision of Plastic Surgery and Hand Surgery, Universitäts Spital Zürich, Zurich, Switzerland.
Pietro GiovanoliDivision of Plastic Surgery and Hand Surgery, Universitäts Spital Zürich, Zurich, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesPatients undergoing reduction mammoplasty (RM) bear the risk of having occult breast cancer nests. The detection rate of malignant neoplasms in the resected specimens, varies greatly in the literature. The aim of our present study was to analyze risk factors and evaluate histopathological findings in our cohort of patients who underwent RM towards our center. MATERIAL AND

methodsIn this retrospective single center study we analyzed 559 female patients [median age 35.99 (±13.34)] who underwent RM between 2000 and 2010. The presence of carcinoma and ductal- (DCIS) or lobular carcinoma in situ (LCIS) were considered as pathological findings. Body mass index (BMI), age, surgical technique and mass of resected tissue were included into the analysis.

resultsThere were 6 cases of occult neoplasia (1.08 %) including 2 cases of breast cancer, one multicentric DCIS and 3 cases of LCIS (0.54 %) in 559 patients. Patients with breast cancer showed a significant increased median age: 49y median (IQR ± 18) vs. 35y (IQR ± 21) (

conclusionsIn our study the occurrence of occult neoplasia was associated with increased age and showed a trend towards increased BMI when compared to patients without pathological findings. The study demonstrates the necessity of thorough medical history, preoperative diagnostic screening and histopathological analysis of all resected specimens.

Indexed as

breast cancerductal carcinoma in situ (DCIS)histopathological analysismammaplastyretrospective studies

Identifiers

PMID29564332
PMCPMC5850823

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