ReviewObstetrics & gynecology science2018
Clinical assessment of the male fertility.
Review in Obstetrics & gynecology science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06147700 (Identifying Molecular Determinants of Infertility in Men), which is not on this map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Identifying Molecular Determinants of Infertility in Men (MODIFY)
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The association between hepatitis B virus and semen quality: a systematic review and meta-analysis.BMC urology · 2024Pooled it
- Heat Stress and the Bull Sperm Transcriptome: Molecular Mechanisms, Fertility, and Epigenetic Inheritance.Animals : an open access journal from MDPI · 2026Review
- Sperm DNA fragmentation and its influence on mammalian reproduction.Nature reviews. Urology · 2026Review
- Epidemiology, Etiopathogenesis, Diagnosis, and Treatment of Male Infertility-Current Trends and Future Directions: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Sperm DNA fragmentation and assisted reproduction: an umbrella meta-analysis.European journal of medical research · 2026Article
- Article
- Conceiving Policy Design: Perspectives From Women Pursuing IVF in British Columbia.Healthcare policy = Politiques de sante · 2025Article
- Epidemiology and occupational risk factors of male infertility based on 3,025 patients in Eastern Morocco during 2021-2023: a cohort study.Obstetrics & gynecology science · 2025Article
- Beta-defensin 126 (DEFB126) localization and expression in the sperms and male reproductive tract of the dromedary camel (Open veterinary journal · 2025Article
- Wuzi-Yanzong-Wan inhibits testicular mitochondrial apoptosis in rats by downregulating TAp73-Mediated P38 MAPK-ADAM17 pathway.Frontiers in pharmacology · 2025Article
- Mitochondrial morphology in fertile and infertile men: image processing and morphometric analysis of the sperm midpiece.Frontiers in cell and developmental biology · 2025Article
- Identification and Functional Analysis of miRNAs in Extracellular Vesicles of Semen Plasma from High- and Low-Fertility Boars.Animals : an open access journal from MDPI · 2024Article
- Tunable motile sperm separation based on sperm persistence in migrating through shear barriers.Biomicrofluidics · 2024Article
- Phospholipase C zeta: a hidden face of sperm for oocyte activation and early embryonic development.Obstetrics & gynecology science · 2024Article
- Differential Proteomic Analysis of Human Sperm: A Systematic Review to Identify Candidate Targets to Monitor Sperm Quality.The world journal of men's health · 2024Article
- The correlation of Septin4 gene expression with sperm quality, DNA damage, and oxidative stress level in infertile patients.Anatomy & cell biology · 2023Article
- The Dutch Pregnancy Drug Register: Suitable to Study Paternal Drug Exposures?International journal of environmental research and public health · 2023Article
- Understanding the Male Perspective: Evaluating Quality of Life and Psychological Distress in Serbian Men Undergoing Infertility Treatment.Life (Basel, Switzerland) · 2023Article
- Sperm selection by the oviduct: perspectives for male fertility and assisted reproductive technologies†.Biology of reproduction · 2023Article
- Analytical Determination of Heavy Metals in Human Seminal Plasma-A Systematic Review.Life (Basel, Switzerland) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The evaluation of infertility in males consists of physical examination and semen analyses. Standardized semen analyses depend on the descriptive analysis of sperm motility, morphology, and concentration, with a threshold level that must be surpassed to be considered a fertile spermatozoon. Nonetheless, these conventional parameters are not satisfactory for clinicians since 25% of infertility cases worldwide remain unexplained. Therefore, newer tests methods have been established to investigate sperm physiology and functions by monitoring characteristics such as motility, capacitation, the acrosome reaction, reactive oxygen species, sperm DNA damage, chromatin structure, zona pellucida binding, and sperm-oocyte fusion. After the introduction of intracytoplasmic sperm injection technique, sperm maturity, morphology, and aneuploidy conditions have gotten more attention for investigating unexplained male infertility. In the present article, recent advancements in research regarding the utilization of male fertility prediction tests and their role and accuracy are reviewed.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.