Evidence map›Paper›PMID 29564176›Full record

ArticleJournal of gastrointestinal oncology2018

Age-related rates of colorectal cancer and the factors associated with overall survival.

Emmanuel Gabriel, Kristopher Attwood, Eisar Al-Sukhni, Deborah Erwin, Patrick Boland, Steven Nurkin

Abstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  18. Age-dependent prognostic value ofFuture oncology (London, England) · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emmanuel GabrielDepartment of Surgery, Section of Surgical Oncology, Mayo Clinic, Jacksonville, FL, USA.
Kristopher AttwoodDepartment of Biostatistics, Roswell Park Cancer Institute, Buffalo, NY, USA.
Eisar Al-SukhniDepartment of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA.
Deborah ErwinDepartment of Epidemiology, Roswell Park Cancer Institute, Buffalo, NY, USA.
Patrick BolandDepartment of Medical Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA.
Steven NurkinDepartment of Surgical Oncology, Roswell Park Cancer Institute, Buffalo, NY, USA.

Funding

Two-Spirit Films in Indigenous Cancer HealthP30CA016056 · NCI · ROSWELL PARK CANCER INSTITUTE CORP · PI Dean G. Tang · 1985 to 2026
$116.6M
NCI NIH HHS P30 CA016056
6 · The paper itself

Abstract

backgroundThe purpose of this study was to identify differences in both demographic and pathologic factors associated with the age-related rates of colorectal cancer (CRC) and overall survival (OS).

methodsThe National Cancer Data Base (NCDB), 2004-2013, was queried for patients with CRC. Patients were stratified by age (≤50

resultsA total of 670,030 patients were included; 488,121 with colon, and 181,909 with rectal or rectosigmoid cancer. For colon cancer, patients ≤50 years had higher proportions of pathologic stage III and IV disease than patients ≥60 (III: 33.7%

conclusionsThere are clear differences in biological factors and in racial and socioeconomic disparities of patients with early onset CRC. Earlier screening should be seriously considered in patients under 50 years who are African-American and Hispanic, as these populations present with more aggressive and advanced disease.

Indexed as

Colorectal cancer (CRC)early onsetNational Cancer Data Base (NCDB)

Identifiers

PMID29564176
PMCPMC5848036

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.