ArticleFungal biology and biotechnology2018
CoIN: co-inducible nitrate expression system for secondary metabolites in
Article in Fungal biology and biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 53 citations in OpenAlex.
- A portable pathway specific transcription factor-promoter circuit enables heterologous production of fungal nonribosomal peptides.Chemical science · 2026Article
- Heterologous Expression Unexpectedly Activates the Host Cryptic Genes inJournal of fungi (Basel, Switzerland) · 2026Article
- Quantitative Characterization of Gene Regulatory Circuits Associated With Fungal Secondary Metabolism to Discover Novel Natural Products.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- A genetic tool to express long fungal biosynthetic genes.Fungal biology and biotechnology · 2023Article
- Total Heterologous Biosynthesis of Fungal Natural Products inJournal of natural products · 2022Review
- Identification of a Bidirectional Promoter fromJournal of fungi (Basel, Switzerland) · 2022Article
- How to Completely Squeeze a Fungus-Advanced Genome Mining Tools for Novel Bioactive Substances.Pharmaceutics · 2022Review
- Development of an auto-inducible expression system by nitrogen sources switching based on the nitrogen catabolite repression regulation.Microbial cell factories · 2022Article
- An Integrated Approach to Determine the Boundaries of the Azaphilone Pigment Biosynthetic Gene Cluster ofFrontiers in microbiology · 2021Article
- A novel fungal gene regulation system based on inducible VPR-dCas9 and nucleosome map-guided sgRNA positioning.Applied microbiology and biotechnology · 2020Article
- In the fungus where it happens: History and future propelling Aspergillus nidulans as the archetype of natural products research.Fungal genetics and biology : FG & B · 2020Article
- Functional characterization of an inducible bidirectional promoter from Fusarium oxysporum f. sp. cubense.Scientific reports · 2020Article
- New Insight Into Pathogenicity and Secondary Metabolism of the Plant PathogenFrontiers in microbiology · 2020Article
- Unearthing fungal chemodiversity and prospects for drug discovery.Current opinion in microbiology · 2019Review
- Fungal secondary metabolism: regulation, function and drug discovery.Nature reviews. Microbiology · 2019Review
- Bidirectional histone-gene promoters inFungal biology and biotechnology · 2019Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundSequencing of fungal species has demonstrated the existence of thousands of putative secondary metabolite gene clusters, the majority of them harboring a unique set of genes thought to participate in production of distinct small molecules. Despite the ready identification of key enzymes and potential cluster genes by bioinformatics techniques in sequenced genomes, the expression and identification of fungal secondary metabolites in the native host is often hampered as the genes might not be expressed under laboratory conditions and the species might not be amenable to genetic manipulation. To overcome these restrictions, we developed an inducible expression system in the genetic model
resultsWe genetically engineered a strain of
conclusionUtilizing one-step yeast recombinational cloning, we developed an inducible expression system in the genetic model
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.