Evidence map›Paper›PMID 29564088›Full record

ArticleAntimicrobial resistance and infection control2018

Reducing rates of

E Casari, C De Luca, M Calabrò, C Scuderi, C Daleno, A Ferrario

Abstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

E CasariMicrobiology Unit, Analysis Laboratory, Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Milan, Italy.
C De LucaMicrobiology Unit, Analysis Laboratory, Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Milan, Italy.
M CalabròMicrobiology Unit, Analysis Laboratory, Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Milan, Italy.
C ScuderiMicrobiology Unit, Analysis Laboratory, Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Milan, Italy.
C DalenoMicrobiology Unit, Analysis Laboratory, Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Milan, Italy.
A FerrarioMicrobiology Unit, Analysis Laboratory, Humanitas Research Hospital, via Manzoni, 56 20089 Rozzano, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Our hospital made a decision to switch from the use of toxin immunoassay to a stand-alone nucleic acid test. This change was accompanied by the provision of clear sampling guidance and rejection criteria and this study aimed to assess the impact of that change. We analysed sample numbers, numbers of positive results, and the proportion of cases assessed as healthcare acquired over a 6-year period during which the testing method was changed from a toxin A/B immunoassay to a stand-alone commercial nucleic acid test after the first two years. Results: Sample numbers and numbers of cases assessed as healthcare acquired fell following the introduction of the nucleic acid test and sampling guidance, while infection rates in other hospitals in the same region remained relatively stable. Conclusions: It is our opinion that the use of a highly sensitive assay together with clear sampling guidance offers the optimal approach to patient management and best use of isolation facilities.

Indexed as

Bacterial ToxinsClostridioides difficileClostridium InfectionsHospitalsHumansImmunoassayNucleic Acid Amplification TechniquesSpecimen HandlingBacterial ToxinsClostridium difficileHospital CDINAAT testPrevention

Identifiers

PMID29564088
PMCPMC5848539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.