Evidence map›Paper›PMID 29564002›Full record

ReviewBeilstein journal of organic chemistry2017

Recent progress in the racemic and enantioselective synthesis of monofluoroalkene-based dipeptide isosteres.

Myriam Drouin, Jean-François Paquin

Open access · diamondAbstract readReview
In one paragraph

Review in Beilstein journal of organic chemistry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 78 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Solid-Phase Synthesis of Gly-Ψ[CH(CFThe Journal of organic chemistry · 2021
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Myriam DrouinDépartement de chimie, Université Laval, 1045 avenue de la Médecine, Pavillon Alexandre-Vachon, Québec (Québec) G1V 0A6, Canada.ORCID 0000-0001-6707-2357
Jean-François PaquinDépartement de chimie, Université Laval, 1045 avenue de la Médecine, Pavillon Alexandre-Vachon, Québec (Québec) G1V 0A6, Canada.ORCID 0000-0003-2412-3083
Université Laval · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monofluoroalkenes are fluorinated motifs that can be used to replace amide bonds. In order to be incorporated into peptides, it is normally necessary to first synthesize a dipeptide where the amide bond has been replaced with a monofluoroalkene. In that context, this review will present the racemic and enantioselective synthesis of monofluoroalkene-based dipeptide isosteres described since 2007. Some applications of those compounds will also be presented.

Indexed as

dipeptide isosteresmonofluoroalkene-based amide bondsmonofluoroalkenespeptidessynthesis

Identifiers

PMID29564002
PMCPMC5753175
OpenAlexW2772621472

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.