Evidence map›Paper›PMID 29563916›Full record

ArticleFrontiers in immunology2018

Old Yellow Enzyme from

Florencia Díaz-Viraqué, María Laura Chiribao, Andrea Trochine, Fabiola González-Herrera, Christian Castillo, Ana Liempi, Ulrike Kemmerling, Juan Diego Maya, Carlos Robello

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Trial
  2. Article
  3. Plants (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Fatty Acid Composition and Metabolism inInternational journal of molecular sciences · 2023
    Review
  8. Article
  9. New Insights into the Role of thePathogens (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Florencia Díaz-ViraquéUnidad de Biología Molecular, Institut Pasteur de Montevideo, Montevideo, Uruguay.
María Laura ChiribaoUnidad de Biología Molecular, Institut Pasteur de Montevideo, Montevideo, Uruguay.
Andrea TrochineUnidad de Biología Molecular, Institut Pasteur de Montevideo, Montevideo, Uruguay.
Fabiola González-HerreraPrograma de Farmacología Molecular y Clínica - ICBM, Facultad de Medicina Universidad de Chile, Santiago de Chile, Chile.
Christian CastilloPrograma de Anatomía y Biología del Desarrollo - ICBM, Facultad de Medicina Universidad De Chile, Santiago de Chile, Chile.
Ana LiempiPrograma de Anatomía y Biología del Desarrollo - ICBM, Facultad de Medicina Universidad De Chile, Santiago de Chile, Chile.
Ulrike KemmerlingPrograma de Anatomía y Biología del Desarrollo - ICBM, Facultad de Medicina Universidad De Chile, Santiago de Chile, Chile.
Juan Diego MayaPrograma de Farmacología Molecular y Clínica - ICBM, Facultad de Medicina Universidad de Chile, Santiago de Chile, Chile.
Carlos RobelloUnidad de Biología Molecular, Institut Pasteur de Montevideo, Montevideo, Uruguay.
Institut Pasteur de Montevideo · UYUniversity of Chile · CLUniversidad de la República · UY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The discovery that trypanosomatids, unicellular organisms of the order Kinetoplastida, are capable of synthesizing prostaglandins raised questions about the role of these molecules during parasitic infections. Multiple studies indicate that prostaglandins could be related to the infection processes and pathogenesis in trypanosomatids. This work aimed to unveil the role of the prostaglandin F

Indexed as

AnimalsChagas DiseaseChlorocebus aethiopsHeLa CellsHumansNADPH DehydrogenaseProstaglandin-Endoperoxide SynthasesProtozoan ProteinsTrypanosoma cruziVero CellsNADPH DehydrogenaseProstaglandin-Endoperoxide SynthasesProtozoan Proteinsbenznidazol and nifurtimox activationdifferentially expressed geneOld Yellow Enzymeprostaglandin F2α synthaseTrypanosoma cruzi

Identifiers

PMID29563916
PMCPMC5845897
OpenAlexW2791236005

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.