ArticleCancer management and research2018
Adenosquamous carcinoma of the bile duct: a population-based study.
Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 22 citations in OpenAlex.
- A Rare Case of Adenosquamous Carcinoma Arising from Intraductal Papillary Neoplasm of the Bile Duct.Surgical case reports · 2026Article
- Differences in Characteristics and Outcome After Hepatic Resection Among Various Types of Mass-Forming Primary Liver Cancer.Indian journal of surgical oncology · 2025Article
- Epidemiology of Adenosquamous Carcinomas.World journal of oncology · 2024Article
- PD-L1 expression in pancreaticobiliary adenosquamous carcinoma: a single-institution case series.Journal of gastrointestinal oncology · 2024Article
- Adenosquamous Carcinoma of Extrahepatic Bile Duct in Primary Sclerosing Cholangitis.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Adenosquamous Carcinoma of the Extrahepatic Bile Duct.Ochsner journal · 2022Article
- A population-based analysis of adenosquamous carcinoma of the salivary gland.Gland surgery · 2021Article
- Case Report: Trastuzumab Treatment in Adenosquamous Carcinoma of the Extrahepatic Biliary Tract With Her-2 Amplification.Frontiers in oncology · 2021Article
- Neoadjuvant radiotherapy improves overall survival for T3/4N+M0 rectal cancer patients: a population-based study of 20300 patients.Radiation oncology (London, England) · 2020Article
- Concomitant adenosquamous carcinoma and cystadenocarcinoma of the extrahepatic bile duct: A case report.World journal of clinical cases · 2019Article
- Adenosquamous Carcinoma of the Stomach: A Population-based Study from the SEER Database.Journal of Cancer · 2019Article
- Basket Trials for Intractable Cancer.Frontiers in oncology · 2019Review
- Development and Validation of a Nomogram for Predicting Specific Mortality Risk After Surgery for Locally Advanced Rectal Cancer: Studies Based on SEER Database and External Validation Cohorts.Cancer control : journal of the Moffitt Cancer CenterArticle
- Adenosquamous Carcinoma of the Distal Common Bile Duct: A Case of a Rare Type of Cholangiocarcinoma.Clinical pathology (Thousand Oaks, Ventura County, Calif.)Article
- Adenosquamous Carcinoma of the Choledochus.Case reports in gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionAdenosquamous carcinoma (ASC) of the bile duct is a rare diagnosis with poorly understood clinicopathological characteristics and disease progression, so identification of the features associated with ASC patient survival is warranted. MATERIALS AND
methodsA population cohort study was performed using prospectively extracted data from the Surveillance, Epidemiology and End Results (SEER) database for patients with histological diagnoses of ASC of the bile duct from 1973 to 2013.
resultsA total of 106 patients with ASC of the bile duct were included (mean age 68.1±13.5 years). Lesions from 58 patients were in the extrahepatic bile duct and 34 were located at the ampulla of Vater. Fifty-seven patients were categorized with a regional stage, 15 had localized disease, and 30 had distant disease. Most (60.4%) patients received cancer-directed surgery, and radiation was performed in 14.1% of cases. The 1-year, 2-year, and 5-year overall survival (OS) for patients with ASC of the bile duct was 30.1%, 11.3%, and 3.7%, respectively. Cancer-directed surgery offered 10 additional months of OS for patients with ASC of the bile duct and median OS was 14.0, 6.0, and 6.0 months for ampulla of Vater, extrahepatic bile duct, and intrahepatic bile duct cases, respectively. A multivariate Cox analysis showed that lesions in the ampulla of Vater (HR=0.51, 95% CI 0.26-0.99) and having surgery (HR=0.34, 95% CI 0.14-0.81) were independent protective prognostic factors for these patients.
conclusionCancer-directed surgery and a primary lesion site of the ampulla of Vater may suggest favorable prognosis for patients with ASC of the bile duct.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.