Evidence map›Paper›PMID 29563815›Full record

ArticleInfection and drug resistance2018

Viability, biofilm formation, and MazEF expression in drug-sensitive and drug-resistant

Ji-Li Zhao, Wei Liu, Wan-Ying Xie, Xu-Dong Cao, Li Yuan

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Review
  2. Article
  3. Identification of Genes Encoded Toxin-Antitoxin System inInfectious disorders drug targets · 2024
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ji-Li Zhao *Department of Pathogenic Biology and Immunology, Medical School of Shihezi University, Shihezi, China.
Wei Liu *Department of Pathogenic Biology and Immunology, Medical School of Shihezi University, Shihezi, China.
Wan-Ying XieDepartment of Pathogenic Biology and Immunology, Medical School of Shihezi University, Shihezi, China.
Xu-Dong CaoDepartment of Pathogenic Biology and Immunology, Medical School of Shihezi University, Shihezi, China.
Li YuanDepartment of Pathogenic Biology and Immunology, Medical School of Shihezi University, Shihezi, China.
Shihezi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTuberculosis (TB) caused by MATERIALS AND

methodsGrowth profiles and biofilm-formation abilities of drug-sensitive, drug-resistant MTB strains and the control strain H37Rv were monitored. Using molecular biology experiments, the mRNA expression of the

resultsEx vivo culture analyses demonstrated that drug-resistant MTB strains exhibit higher survival rates than drug-sensitive strains and the control strain H37Rv. However, there was no statistical difference in biofilm-formation ability in the drug-sensitive, drug-resistant, and H37Rv strains.

conclusionThe increased viability of MTB drug-resistant strains compared with drug-sensitive strains is likely to be related to differential MazEF mRNA and protein expression.

Indexed as

apoptosisbiofilmdrug resistanceMycobacterium tuberculosistoxin–antitoxin systemviability

Identifiers

PMID29563815
PMCPMC5846055
OpenAlexW2791098613

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.