Trial reportClinical interventions in aging2018
Relationship between enteral nutrition and serum levels of inflammatory factors and cardiac function in elderly patients with heart failure.
Trial report in Clinical interventions in aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.
- Nutrition in chronic heart failure patients: a systematic review.Heart failure reviews · 2020Pooled it
- Impact of Angiotensin Receptor-Neprilysin Inhibition Combined with Enteral Nutritional Therapy on Cardiac Performance and Inflammatory Burden in Hemodialysis-Associated Heart Failure: Clinical and Experimental Evidence.Malawi medical journal : the journal of Medical Association of Malawi · 2026Trial
- Economic Evaluation of Individualized Nutritional Support for Hospitalized Patients with Chronic Heart Failure.Nutrients · 2022Trial
- Effects of Enhanced Nutritional Care in Heart Failure - A Systematic Review and Meta-Analysis.Circulation reports · 2026Review
- Association between geriatric nutritional risk index and risk of heart failure: a cross-sectional study.BMC cardiovascular disorders · 2025Article
- Association of Immune Nutrition Indices with the Risk of All-Cause Mortality and Cardiovascular Mortality in Patients with Heart Failure in the NHANES (1999-2018).Reviews in cardiovascular medicine · 2025Article
- Prognostic impact of CONUT score in older patients with chronic heart failure.BMC geriatrics · 2024Article
- Oral nutritional supplements in older outpatients with heart failure: rationale and design of the ALIMENT-HF trial.ESC heart failure · 2024Article
- Nutritional Interventions in Older, Frail Persons with Heart Failure-A Systematic Narrative Review.JAR life · 2024Review
- Geriatric Nutritional Risk Index Predicts High Activities of Daily Living at Discharge in Older Patients with Heart Failure after Cardiac Rehabilitation.Journal of clinical medicine · 2023Article
- Change in Nutritional Status during Hospitalization and Prognosis in Patients with Heart Failure with Preserved Ejection Fraction.Nutrients · 2022Article
- The Anti-inflammatory Effect of Chitosan Oligosaccharide on Heart Failure in Mice.BioMed research international · 2022Article
- Guidelines for parenteral and enteral nutrition in geriatric patients in China.Aging medicine (Milton (N.S.W)) · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo investigate enteral nutrition's effect on serum inflammatory factors and the cardiac function of malnourished elderly patients with heart failure. PATIENTS AND
methodsA total of 105 elderly patients with heart failure were randomly divided into 3 groups: Treatment Group A, Treatment Group B, and the Control Group (Group C), each group having 35 patients and being administered conventional heart failure treatment. Group A was treated with 500 mL·d
resultsAfter the treatment, the body mass index, skinfold thickness of upper arm triceps, muscle circumference of the upper arm, upper arm muscle circumference, total protein, albumin, hemoglobin, and left ventricular ejection fraction in the treatment groups all increased, with relatively obvious relief of symptoms of heart failure. The levels of B-type natriuretic peptide, interleukin-6, tumor necrosis factor-α, and C-reactive protein all rose to different extents (
conclusionThe use of enteral nutrition in conventional treatment of elderly patients with heart failure could improve not only patients' nutritional status and cardiac function, but also their immune function, thus reducing the levels of inflammatory factors. The longer the treatment period is, the more obvious the improvement in patients' cardiac function and inflammatory factors will be observed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.