Evidence map›Paper›PMID 29563590›Full record

Trial reportBone marrow transplantation2018

Successful outcomes of second hematopoietic stem cell transplantation with total nodal irradiation and ATG conditioning for graft failure in adult patients with severe aplastic anemia.

Seung-Ah Yahng, Sung-Soo Park, Young-Woo Jeon, Jae-Ho Yoon, Seung-Hwan Shin, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee and 6 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Bone marrow transplantation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. [Tumor necrosis factor-α and transforming growth factor-βNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Seung-Ah YahngDepartment of Hematology, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
Sung-Soo ParkDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Young-Woo JeonDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID http://orcid.org/0000-0003-3362-8200
Jae-Ho YoonDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seung-Hwan ShinDepartment of Hematology, Yeoido St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID http://orcid.org/0000-0002-8472-7041
Sung-Eun LeeDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Byung-Sik ChoDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Ki-Seong EomDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Yoo-Jin KimDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seok LeeDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Chang-Ki MinDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Hee-Je KimDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seok-Goo ChoDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.ORCID http://orcid.org/0000-0002-5429-4839
Dong-Wook KimDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Woo-Sung MinDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Jong Wook LeeDepartment of Hematology, Catholic Blood and Marrow Transplantation Center, Seoul. St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. jwlee@catholic.ac.kr.
The Catholic University of Korea Seoul St. Mary's Hospital · KRThe Catholic University of Korea Incheon St. Mary's Hospital · KRThe Catholic University of Korea Yeouido St. Mary's Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data regarding the optimal approach for second allogeneic hematopoietic stem cell transplantation (HSCT) after graft failure (GF) in acquired severe aplastic anemia (SAA) are still limited and heterogeneous. We examined 24 patients who underwent second HLA-matched sibling donor (MSD) peripheral blood HSCT for GF. The reconditioning regimen (TNI-750/ATG) consisted of a single dose of total nodal irradiation (TNI, 750 cGy) and antithymocyte globulin (ATG; Thymoglobulin

Indexed as

Anemia, AplasticCombined Modality TherapyGraft RejectionGraft vs Host DiseaseHematopoietic Stem Cell TransplantationAdolescentAdultAllograftsAntilymphocyte SerumDisease-Free SurvivalFemaleHumansMaleMiddle AgedSeverity of Illness IndexSiblingsAntilymphocyte Serumthymoglobulin

Identifiers

PMID29563590
OpenAlexW2789821322

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.