ArticleScientific reports2018
Profiling walking dysfunction in multiple sclerosis: characterisation, classification and progression over time.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06672484 (Gait and Cortical Activity Profile of People With Multiple Sclerosis Presenting With Walking Fatigability), which is not on this map. Cited by 67 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Gait and Cortical Activity Profile of People With Multiple Sclerosis Presenting With Walking Fatigability
Who cites it
67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 129 citations in OpenAlex.
- Characterizing gait in people with multiple sclerosis using digital data from smartphone sensors: A proposed framework.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025Pooled it
- Neural correlates of dual-task walking in people with central neurological disorders: a systematic review.Journal of neurology · 2022Pooled it
- Outcome measures used in trials on gait rehabilitation in multiple sclerosis: A systematic literature review.PloS one · 2021Pooled it
- The Effectiveness of Guided Imagery on Walking and Balance Dysfunction in Patients With Multiple Sclerosis: A Randomized Controlled Trial.Behavioural neurology · 2025Trial
- Detrended fluctuation analysis of gait dynamics when entraining to music and metronomes at different tempi in persons with multiple sclerosis.Scientific reports · 2020Trial
- Familiarization with treadmill walking: How much is enough?Scientific reports · 2019Trial
- Changes in temporal and spatial gait coordination during the six‑minute walk test in people with multiple sclerosis.Medical & biological engineering & computing · 2026Article
- The cost of imbalance: how balance problems drive energy cost of walking in persons with multiple sclerosis.Journal of rehabilitation medicine · 2026Article
- Trunk and lower limb kinematic alterations during the forward step-down task in women with multiple sclerosis: a comparative 3D motion analysis.Journal of neuroengineering and rehabilitation · 2026Article
- Quantifying mutual hesitation and identifying kinematic predictors in near-collision avoidance in walking.Scientific reports · 2026Article
- Estimation of walking energy expenditure using a single sacrum-mounted IMU based on biomechanically-informed machine learning.Scientific reports · 2025Article
- Concordance of Wearable Sensors and Depth Cameras for Quantitative Gait Assessment in Multiple Sclerosis.Multiple sclerosis and related disorders · 2025Article
- Validation of the Chinese version of the 12-Item multiple sclerosis walking scale in individuals with multiple sclerosis: a psychometric and item response theory analysis.BMC psychology · 2025Article
- Joint Kinematics and Gait Pattern in Multiple Sclerosis: A 3D Analysis Comparative Approach.Bioengineering (Basel, Switzerland) · 2025Article
- Phenotyping and characterising gait profiles of people with multiple sclerosis.Scientific reports · 2025Article
- Digital biomechanical assessment of gait in patients with peripheral neuropathies.Journal of neuroengineering and rehabilitation · 2025Article
- Quantification of Lower Limb Kinematics During Swimming in Individuals with Spinal Cord Injury.Sensors (Basel, Switzerland) · 2025Article
- A Delphi study to identify key gait patterns and their potential causes in people with multiple sclerosis.Journal of rehabilitation medicine · 2025Article
- A Task-Agnostic Approach to Unified Multi-Activity Gait Phase Estimation via Bilateral Sensing.IEEE ... International Conference on Rehabilitation Robotics : [proceedings] · 2025Article
- Effects of Physical Exercise on Neurofilament Light Chain and Glial Fibrillary Acidic Protein Level in Patients with Multiple Sclerosis: A Systematic Review and Bayesian Network Meta-Analysis.Journal of clinical medicine · 2025Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gait dysfunction is a common and relevant symptom in multiple sclerosis (MS). This study aimed to profile gait pathology in gait-impaired patients with MS using comprehensive 3D gait analysis and clinical walking tests. Thirty-seven patients with MS walked on the treadmill at their individual, sustainable speed while 20 healthy control subjects walked at all the different patient's paces, allowing for comparisons independent of walking velocity. Kinematic analysis revealed pronounced restrictions in knee and ankle joint excursion, increased gait variability and asymmetry along with impaired dynamic stability in patients. The most discriminative single gait parameter, differentiating patients from controls with an accuracy of 83.3% (χ
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.